Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | SIGMAR1 | Q99720 | 2/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.44 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.44 |
| ▸ | PKM | P14618 | 1/20 | 0.44 |
| ▸ | P4HB | P07237 | 1/20 | 0.43 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.43 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.43 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8858065 | 0.95 | LMNA (0.44) | LMNAKMT2AMEN1L3MBTL1SIGMAR1 | |
| SCHEMBL7316074 | 0.95 | ALDH1A1 (0.47) | LMNAKMT2AMEN1L3MBTL1SIGMAR1 | |
| SCHEMBL7307187 | 0.95 | LMNA (0.46) | LMNAKMT2AMEN1L3MBTL1SIGMAR1 | |
| SCHEMBL8858111 | 0.93 | LMNA (0.41) | LMNAKMT2AMEN1L3MBTL1SIGMAR1 | |
| SCHEMBL8858177 | 0.91 | ALDH1A1 (0.43) | LMNAKMT2AMEN1L3MBTL1SIGMAR1 | |
| SCHEMBL8858137 | 0.91 | LMNA (0.42) | LMNAKMT2AMEN1L3MBTL1SIGMAR1 | |
| SCHEMBL7306280 | 0.91 | LMNA (0.45) | LMNAKMT2AMEN1L3MBTL1SIGMAR1 | |
| SCHEMBL7309383 | 0.89 | LMNA (0.47) | LMNAKMT2AMEN1L3MBTL1SIGMAR1 | |
| SCHEMBL7317133 | 0.89 | LMNA (0.44) | LMNAKMT2AMEN1L3MBTL1SIGMAR1 | |
| SCHEMBL7306793 | 0.89 | LMNA (0.43) | LMNAKMT2AMEN1L3MBTL1SIGMAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0727425-A1 | Adhesion receptor antagonists | MERCK PATENT GmbH (DE) | 1996-08-21 | — | — | EP | disclosed |