SCHEMBL7316554

SCHEMBL7316554

C=c1c(=O)[nH]c2n1Cc1c(cc(F)cc1OCCCC(=O)N(CCCCC)CCCCC)N=2

nearest known ligand 0.46

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PDE3B Q13370 2/20 0.46
PDE3A Q14432 2/20 0.46

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7308929 0.80 PDE3B (0.44) PDE3BPDE3A
SCHEMBL7318804 0.79 PDE3B (0.41) PDE3BPDE3A
SCHEMBL7311494 0.78 PDE3B (0.52) PDE3BPDE3A
SCHEMBL7319049 0.77 PDE3B (0.48) PDE3BPDE3A
SCHEMBL7311914 0.75 PDE3B (0.51) PDE3BPDE3A
SCHEMBL7317096 0.75 PDE3B (0.61) PDE3BPDE3A
SCHEMBL7308920 0.73 PDE3B (0.43) PDE3BPDE3A
SCHEMBL7311818 0.72 PDE3B (0.45) PDE3BPDE3A
SCHEMBL7312258 0.72 PDE3B (0.42) PDE3BPDE3A
SCHEMBL7319721 0.70 PDE3B (0.56) PDE3BPDE3A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4670434-A ANTICOAGULANT, INOTROPIC AGENT SYNTEX (U.S.A.) INC. (US) 1987-06-02 US disclosed