Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 3/20 | 0.44 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | MAPT | P10636 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | TSPO | P30536 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
| ▸ | THPO | P40225 | 1/20 | 0.31 |
| ▸ | MTOR | P42345 | 1/20 | 0.31 |
| ▸ | BLM | P54132 | 1/20 | 0.31 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.31 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7308920 | 0.87 | PDE3B (0.43) | PDE3BPDE3A | |
| SCHEMBL7316554 | 0.80 | PDE3B (0.46) | PDE3BPDE3A | |
| SCHEMBL7313595 | 0.79 | PDE3B (0.68) | PDE3BPDE3A | |
| SCHEMBL7314185 | 0.79 | PDE3B (0.48) | PDE3BPDE3A | |
| SCHEMBL7318804 | 0.76 | PDE3B (0.41) | PDE3BPDE3AKDM4EALDH1A1CYP1A2 | |
| SCHEMBL7311818 | 0.72 | PDE3B (0.45) | PDE3BPDE3AKDM4EMEN1ALDH1A1 | |
| SCHEMBL7309784 | 0.72 | PDE3B (0.54) | PDE3BPDE3A | |
| SCHEMBL7317096 | 0.72 | PDE3B (0.61) | PDE3BPDE3ATSHRHSD17B10 | |
| SCHEMBL7319304 | 0.71 | PDE3B (0.49) | PDE3BPDE3A | |
| SCHEMBL7319732 | 0.71 | PDE3B (0.42) | PDE3BPDE3AKDM4EALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |