Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PRCP | P42785 | 1/20 | 0.45 |
| ▸ | FKBP1A | P62942 | 3/20 | 0.44 |
| ▸ | F2 | P00734 | 2/20 | 0.44 |
| ▸ | DPP4 | P27487 | 2/20 | 0.44 |
| ▸ | ACE | P12821 | 3/20 | 0.44 |
| ▸ | ACE2 | Q9BYF1 | 3/20 | 0.44 |
| ▸ | CHRM3 | P20309 | 3/20 | 0.44 |
| ▸ | ITGB1 | P05556 | 4/20 | 0.43 |
| ▸ | ITGA4 | P13612 | 4/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.43 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.42 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.42 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.42 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7305485 | 0.92 | FKBP1A (0.53) | FKBP1AF2DPP4ITGB1ITGA4 | |
| SCHEMBL7305475 | 0.92 | FKBP1A (0.53) | FKBP1AF2DPP4ITGB1ITGA4 | |
| SCHEMBL7308546 | 0.92 | CHRM3 (0.44) | FKBP1AF2DPP4CHRM3ITGB1 | |
| SCHEMBL7308557 | 0.92 | CHRM3 (0.44) | FKBP1AF2DPP4CHRM3ITGB1 | |
| SCHEMBL7309517 | 0.91 | FKBP1A (0.51) | PRCPFKBP1AF2ITGB1ITGA4 | |
| SCHEMBL7309531 | 0.91 | FKBP1A (0.51) | PRCPFKBP1AF2ITGB1ITGA4 | |
| SCHEMBL7301358 | 0.91 | FKBP1A (0.47) | FKBP1AF2DPP4CHRM3ITGB1 | |
| SCHEMBL7301363 | 0.91 | FKBP1A (0.47) | FKBP1AF2DPP4CHRM3ITGB1 | |
| SCHEMBL7306032 | 0.89 | F2 (0.49) | FKBP1AF2CHRM3PRSS1 | |
| SCHEMBL7306042 | 0.89 | F2 (0.49) | FKBP1AF2CHRM3PRSS1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1041064-A2 | N-substituted alpha aminoacid amides as calcium channel modulators | ELI LILLY AND COMPANY LIMITED (GB) | 2000-10-04 | — | — | EP | disclosed |
| EP-0805147-A1 | Novel N-substituted alpha aminoacid amides as calcium channel modulators | LILLY INDUSTRIES LIMITED (GB) | 1997-11-05 | — | — | EP | disclosed |