SCHEMBL731658

SCHEMBL731658

C=CO/C(=C/C(=O)O)C(=O)O

nearest known ligand 0.38

Predicted protein targets (top 5)

geneUniProtsupporting neighboursconfidence
LMNA P02545 1/20 0.38
KDM4E B2RXH2 1/20 0.32
TSHR P16473 1/20 0.32
ALOX15 P16050 1/20 0.30
HSD17B10 Q99714 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL21291677 1.00 LMNA (0.38) LMNAKDM4ETSHRALOX15HSD17B10
SCHEMBL18985163 0.77
SCHEMBL16728944 0.75
SCHEMBL221900 0.72 TSHR (0.35) KDM4ETSHR
SCHEMBL221385 0.72 TSHR (0.35) KDM4ETSHR
SCHEMBL5498850 0.72 TSHR (0.35) KDM4ETSHR
SCHEMBL133163 0.72 GRIK1 (0.33) LMNATSHRALOX15HSD17B10
SCHEMBL4562012 0.72
SCHEMBL542266 0.70 HCAR2 (0.40) KDM4ETSHR
SCHEMBL542268 0.70 HCAR2 (0.40) KDM4ETSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 67 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1966842-B1 Lighting elements and devices LOMOX LTD (GB) 2019-08-28 EP claimed
CN-109689216-A Protective surface coating for flow cell 伊鲁米那股份有限公司 2019-04-26 CN claimed
CN-103687830-B Method and additive for improving adhesion of a composition to a substrate 阿克佐诺贝尔化学国际公司 2016-08-17 CN claimed
CN-102781869-B Method and additive for improving adhesion of building compositions to substrates AKZO NOBEL CHEMICALS INTERNATIONAL B.V. (NL) 2015-08-05 CN claimed
CN-103415538-B Method for producing polymers by emulsion or suspension polymerization in a jet loop reactor WACKER CHEMIE AG 2015-07-15 CN claimed
CN-107257824-B Aqueous dispersion or polymer blend in the form of a powder which can be redispersed in water WACKER CHEMIE AG (DE) 2019-11-01 CN disclosed
CN-106511112-B A kind of persistently refrigerant antibacterial toothpaste and preparation method thereof 美晨集团股份有限公司 2019-10-18 CN disclosed
CN-110325598-A Curable thermoset resin composition with improved mechanical performance 赢创罗姆有限公司 2019-10-11 CN disclosed
CN-106491390-B A kind of persistently refrigerant antibacterial oral cavity cleaning and nursing liquid and preparation method thereof 美晨集团股份有限公司 2019-09-03 CN disclosed
EP-1966842-B1 Lighting elements and devices LOMOX LTD (GB) 2019-08-28 EP disclosed
CN-109689216-A Protective surface coating for flow cell 伊鲁米那股份有限公司 2019-04-26 CN disclosed
CN-109196002-A Fine and the inorganic salt copolymer of uniform methyl vinyl ether-maleic acid and its purposes in oral care and medicinal application 博爱新开源医疗科技集团股份有限公司 2019-01-11 CN disclosed
EP-1945694-A1 NOVEL WATER-BASED ADHESIVES FOR INDUSTRIAL APPLICATIONS National Starch and Chemical Investment Holding Corporation (US) 2008-07-23 EP disclosed
WO-2008031537-A1 POWDER AND WATER-BASED ADHESIVE COMPOSITION HENKEL AG & CO, KGAA (DE) 2008-03-20 WO disclosed
EP-1897926-A1 Powder and water-based adhesive composition National Starch and Chemical Investment Holding Corporation (US) 2008-03-12 EP disclosed
WO-2007031211-A1 NOVEL WATER-BASED ADHESIVES FOR INDUSTRIAL APPLICATIONS NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) 2007-03-22 WO disclosed
WO-2006002297-A1 PROCESS TO GENERATE WATER BASED ADHESIVES AND THEIR USE NATIONAL STARCH AND CHEMICAL INVESTMENT HOLDING CORPORATION (US) 2006-01-05 WO disclosed
EP-1609834-A1 Process to generate water based adhesives and their use National Starch and Chemical Investment Holding Corporation (US) 2005-12-28 EP disclosed
EP-0089230-A1 Silver halide photographic material KONICA CORPORATION (JP) 1983-09-21 EP disclosed
EP-0089231-A1 Silver halide photographic material KONICA CORPORATION (JP) 1983-09-21 EP disclosed