Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 3/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
| ▸ | EGLN1 | Q9GZT9 | 1/20 | 0.30 |
| ▸ | EGLN3 | Q9H6Z9 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL221900 | 1.00 | TSHR (0.35) | TSHRKDM4ETP53EGLN1EGLN3 | |
| SCHEMBL5498850 | 1.00 | TSHR (0.35) | TSHRKDM4ETP53EGLN1EGLN3 | |
| SCHEMBL542267 | 0.74 | HCAR2 (0.40) | TSHRKDM4E | |
| SCHEMBL542268 | 0.74 | HCAR2 (0.40) | TSHRKDM4E | |
| SCHEMBL542266 | 0.74 | HCAR2 (0.40) | TSHRKDM4E | |
| SCHEMBL21291677 | 0.72 | LMNA (0.38) | TSHRKDM4E | |
| SCHEMBL731658 | 0.72 | LMNA (0.38) | TSHRKDM4E | |
| SCHEMBL11129144 | 0.70 | HCAR2 (0.32) | TSHRKDM4E | |
| SCHEMBL29022487 | 0.70 | HCAR2 (0.32) | TSHRKDM4E | |
| SCHEMBL7745871 | 0.70 | TSHR (0.43) | TSHRKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 44 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3080610-A1 | UNIVERSAL ANTIGEN RETRIEVAL COMPOUNDS AND METHODS OF USE | University of Houston System (US) | 2016-10-19 | — | — | EP | claimed |
| CN-106030309-A | Universal antigen retrieval compounds and methods of use thereof | 休斯敦大学系统 | 2016-10-12 | — | — | CN | claimed |
| US-20150168417-A1 | Universal Antigen Retrieval Compounds and Methods of Use | UNIVERSITY OF HOUSTON SYSTEM (US) | 2015-06-18 | — | — | US | claimed |
| WO-2015088667-A1 | UNIVERSAL ANTIGEN RETRIEVAL COMPOUNDS AND METHODS OF USE | UNIVERSITY OF HOUSTON SYSTEM (US) | 2015-06-18 | — | — | WO | claimed |
| US-20050090668-A1 | Preparation of 5-hydroxy-6-oxo-1,6-dihydropyrimidine compounds | DREHER SPENCER D (US) | 2005-04-28 | — | — | US | claimed |
| US-6849705-B2 | Bifunctional polyaddition compounds as crosslinkers for polyurethane powder coatings | DEGUSSA AG (DE) | 2005-02-01 | — | — | US | claimed |
| US-20030212239-A1 | Bifunctional polyaddition compounds as crosslinkers for polyurethane powder coatings | DEGUSSA AG (DE) | 2003-11-13 | — | — | US | claimed |
| EP-3315968-B1 | UNIVERSAL ANTIGEN RETRIEVAL COMPOUNDS AND METHODS OF USE | UNIV HOUSTON SYSTEM (US) | 2025-10-15 | — | — | EP | disclosed |
| WO-2024071123-A1 | EASILY ADHESIVE POLYAMIDE FILM AND METHOD FOR PRODUCING SAME | ユニチカ株式会社 | 2024-04-04 | — | — | WO | disclosed |
| CN-117777396-A | Heat-sealable aqueous resin composition and laminate | 荒川化学工业株式会社 | 2024-03-29 | — | — | CN | disclosed |
| US-20240101818-A1 | AQUEOUS HEAT-SEALABLE RESIN COMPOSITION AND LAMINATE | ARAKAWA CHEMICAL INDUSTRIES, LTD. (JP) | 2024-03-28 | — | — | US | disclosed |
| US-20230077630-A1 | WATER-BASED COMPOSITION FOR BARRIER AND LAMINATED MATERIAL | ARAKAWA CHEMICAL INDUSTRIES, LTD. (JP) | 2023-03-16 | — | — | US | disclosed |
| CN-115725231-A | Water-based composition for barrier and laminate | 荒川化学工业株式会社 | 2023-03-03 | — | — | CN | disclosed |
| US-6849705-B2 | Bifunctional polyaddition compounds as crosslinkers for polyurethane powder coatings | DEGUSSA AG (DE) | 2005-02-01 | — | — | US | disclosed |
| US-20030212239-A1 | Bifunctional polyaddition compounds as crosslinkers for polyurethane powder coatings | DEGUSSA AG (DE) | 2003-11-13 | — | — | US | disclosed |
| US-6313196-B1 | FOR INK JET PRINTING; SMUDGE RESISTANCE | AGFA-GEVAERT (BE) | 2001-11-06 | — | — | US | disclosed |
| US-5693737-A | POLYETHERURETHANES FOR PREPARING CREASE-RESISTANT TEXTILES | BAYER AKTIENGESELLSCHAFT (DE) | 1997-12-02 | — | — | US | disclosed |
| US-5607482-A | BLOCKED POLYISOCYANATE | BAYER AKTIENGESELLSCHAFT (DE) | 1997-03-04 | — | — | US | disclosed |
| US-5508370-A | POLYETHERURETHANE COPOLYMER; TEXTILE FINISH | BAYER AKTIENGESELLSCHAFT (DE) | 1996-04-16 | — | — | US | disclosed |
| US-4544683-A | GYPSUM-POLYURETHANE OR POLYURETHANE-POLYUREA | BAYER AKTIENGESELLSCHAFT (DE) | 1985-10-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20050090668-A1 | Preparation of 5-hydroxy-6-oxo-1,6-dihydropyrimidine compounds | DPYD, DHODH, DHPS | TSHR 4498/4885KDM4E 1806/4885TP53 1209/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.