Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.64 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.62 |
| ▸ | DRD4 | P21917 | 3/20 | 0.59 |
| ▸ | MEN1 | O00255 | 1/20 | 0.59 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.59 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.59 |
| ▸ | SCN8A | Q9UQD0 | 1/20 | 0.58 |
| ▸ | SIGMAR1 | Q99720 | 3/20 | 0.58 |
| ▸ | GAA | P10253 | 1/20 | 0.52 |
| ▸ | MAPT | P10636 | 1/20 | 0.52 |
| ▸ | DRD2 | P14416 | 1/20 | 0.51 |
| ▸ | DRD3 | P35462 | 1/20 | 0.51 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.51 |
| ▸ | PPARG | P37231 | 1/20 | 0.50 |
| ▸ | BCHE | P06276 | 1/20 | 0.49 |
| ▸ | MPO | P05164 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL893154 | 0.81 | MAOA (0.86) | MAOACHRM2DRD4MEN1KMT2A | |
| SCHEMBL4932707 | 0.81 | MAOA (0.95) | MAOACHRM2MEN1KMT2ATDP1 | |
| SCHEMBL7316643 | 0.81 | MAOA (0.64) | MAOACHRM2DRD4MEN1KMT2A | |
| SCHEMBL15341674 | 0.79 | MAOA (0.62) | MAOACHRM2DRD4MEN1KMT2A | |
| Hydrochloric Acid SCHEMBL11130174 | 0.79 | DRD4 (0.79) | MAOACHRM2DRD4KMT2ASCN8A | |
| SCHEMBL8851048 | 0.79 | MAOA (1.00) | MAOACHRM2MEN1KMT2ATDP1 | |
| SCHEMBL16260102 | 0.79 | MAOA (1.00) | MAOACHRM2MEN1KMT2ATDP1 | |
| SCHEMBL4642587 | 0.79 | MAOA (1.00) | MAOACHRM2MEN1KMT2ATDP1 | |
| SCHEMBL7202099 | 0.79 | MAOA (1.00) | MAOACHRM2MEN1KMT2ATDP1 | |
| Hydrochloric Acid SCHEMBL3524869 | 0.79 | MAOA (0.82) | MAOACHRM2DRD4MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4918074-A | CALCIUM ANTAGONISTS | YOSHITOMI PHARMACEUTICAL INDUSTRIES, LTD. (JP) | 1990-04-17 | — | — | US | disclosed |
| EP-0217142-A2 | A polyazaheterocyclic compound | Yoshitomi Pharmaceutical Industries, Ltd. (JP) | 1987-04-08 | — | — | EP | disclosed |