Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.95 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.91 |
| ▸ | SIGMAR1 | Q99720 | 7/20 | 0.83 |
| ▸ | MEN1 | O00255 | 1/20 | 0.80 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.80 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.80 |
| ▸ | GAA | P10253 | 1/20 | 0.67 |
| ▸ | MAPT | P10636 | 1/20 | 0.67 |
| ▸ | HDAC3 | O15379 | 2/20 | 0.63 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.63 |
| ▸ | HDAC2 | Q92769 | 2/20 | 0.63 |
| ▸ | HDAC8 | Q9BY41 | 2/20 | 0.63 |
| ▸ | NCOR2 | Q9Y618 | 2/20 | 0.63 |
| ▸ | MPO | P05164 | 1/20 | 0.60 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8644839 | 0.97 | MAOA (1.00) | MAOACHRM2SIGMAR1MEN1KMT2A | |
| SCHEMBL4642587 | 0.97 | MAOA (1.00) | MAOACHRM2SIGMAR1MEN1KMT2A | |
| SCHEMBL29361832 | 0.97 | MAOA (1.00) | MAOACHRM2SIGMAR1MEN1KMT2A | |
| SCHEMBL8851048 | 0.97 | MAOA (1.00) | MAOACHRM2SIGMAR1MEN1KMT2A | |
| SCHEMBL16260102 | 0.97 | MAOA (1.00) | MAOACHRM2SIGMAR1MEN1KMT2A | |
| SCHEMBL7202099 | 0.97 | MAOA (1.00) | MAOACHRM2SIGMAR1MEN1KMT2A | |
| SCHEMBL8024796 | 0.95 | CHRM2 (0.91) | MAOACHRM2SIGMAR1MEN1KMT2A | |
| SCHEMBL8021930 | 0.95 | CHRM2 (1.00) | MAOACHRM2SIGMAR1MEN1KMT2A | |
| SCHEMBL8021157 | 0.95 | CHRM2 (1.00) | MAOACHRM2SIGMAR1MEN1KMT2A | |
| SCHEMBL31194846 | 0.95 | MAOA (0.95) | MAOACHRM2SIGMAR1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 39 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5677350-A | Inhibition of cancer cell growth, proliferation, and metastasis using N,N'-dα,ω-diaminoalkanes | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1997-10-14 | — | — | US | claimed |
| WO-1996040096-A1 | INHIBITION OF CANCER CELL GROWTH, PROLIFERATION AND METASTASIS USING N,N'-DIBENZYL-α,φ-DIAMINOALKANES | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1996-12-19 | — | — | WO | claimed |
| EP-4257581-A1 | METHODS FOR PRODUCING (6S,15S)-3,8,13,18-TETRAAZAICOSANE-6,15-DIOL | PANBELA THERAPEUTICS, INC. (US) | 2023-10-11 | — | — | EP | disclosed |
| EP-3746425-B1 | METHODS FOR PRODUCING (6S,15S)-3,8,13,18-TETRAAZAICOSANE-6,15-DIOL | PANBELA THERAPEUTICS INC (US) | 2023-08-02 | — | — | EP | disclosed |
| US-11591286-B2 | Methods for producing (6S,15S)-3,8,13,18-tetraazaicosane-6,15-diol | Panbela Therapeutics, Inc. (US) | 2023-02-28 | — | — | US | disclosed |
| US-11591286-B2 | Methods for producing (6S,15S)-3,8,13,18-tetraazaicosane-6,15-diol | Panbela Therapeutics, Inc. (US) | 2023-02-28 | — | — | US | disclosed |
| US-20220009877-A1 | METHODS FOR PRODUCING (6S,15S)-3,8,13,18-TETRAAZAICOSANE-6,15-DIOL | CREATIVE PLANNING BUSINESS ALLIANCE LLC | 2022-01-13 | — | — | US | disclosed |
| US-20210009504-A1 | METHODS FOR PRODUCING (6S,15S)-3,8,13,18-TETRAAZAICOSANE-6,15-DIOL | Panbela Therapeutics, Inc. | 2021-01-14 | — | — | US | disclosed |
| WO-2019152373-A1 | METHODS FOR PRODUCING (6S,15S)-3,8,13,18-TETRAAZAICOSANE-6,15-DIOL | SUN BIOPHARMA, INC. (US) | 2019-08-08 | — | — | WO | disclosed |
| EP-0829463-B2 | Process for preparing an (E)-(R)-2-alkyl-4-(2,2,3-trimethylcyclopent-3-en-1-yl)-2-buten-1-ol | TAKASAGO PERFUMERY CO LTD (JP) | 2008-11-05 | — | — | EP | disclosed |
| US-20080108706-A1 | Chemical resection of pancreas | BERGERON RAYMOND J JR | 2008-05-08 | — | — | US | disclosed |
| US-5750804-A | HYDROGENATING 3-ISOCAMPHYLCYCLOHEXANONE USING RUTHENIUM/PHOSPHINE COMPLEX CATALYST IN PRESENCE OF ALKALI METAL OR ALKALINE EARTH METAL AND AMINE BASE | TAKASAGO INTERNATIONAL CORPORATION (JP) | 1998-05-12 | — | — | US | disclosed |
| EP-0829463-A2 | (E)-(R)-2-Alkyl-4-(2,2,3-trimethylcyclopent-3-en-1-yl)-2-buten-1-ol, process for preparing the same, and use thereof in perfume compositions | Takasago International Corporation (JP) | 1998-03-18 | — | — | EP | disclosed |
| US-5677350-A | Inhibition of cancer cell growth, proliferation, and metastasis using N,N'-dα,ω-diaminoalkanes | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1997-10-14 | — | — | US | disclosed |
| WO-1996040096-A1 | INHIBITION OF CANCER CELL GROWTH, PROLIFERATION AND METASTASIS USING N,N'-DIBENZYL-α,φ-DIAMINOALKANES | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 1996-12-19 | — | — | WO | disclosed |
| US-4179469-A | Preparation of amines | UOP INC. (US) | 1979-12-18 | — | — | US | disclosed |
| US-4120957-A | ANTHELMINTICS | ROHM AND HAAS COMPANY (US) | 1978-10-17 | — | — | US | disclosed |
| US-4024281-A | N,N-bis[2-(3-substituted-4-hydroxyphenyl)-ethyl or -2-hydroxyethyl]-polymethylenediamines | SMITHKLINE CORPORATION (US) | 1977-05-17 | — | — | US | disclosed |
| US-4021485-A | BRONCHOSPASMOLYTICS, ANTIPRURITICS, ANTIALLERGICS | BOEHRINGER INGELHEIM GMBH (DT) | 1977-05-03 | — | — | US | disclosed |
| US-3933913-A | N,N'-bis[3-substituted-4-hydroxypheyl)-2-hydroxyethyl)]-polymethylenediamines | SMITHKLINE CORPORATION (US) | 1976-01-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11591286-B2 | Methods for producing (6S,15S)-3,8,13,18-tetraazaicosane-6,15-diol | DHPS, LSS, HSD17B12 | MAOA 720/4885CHRM2 4667/4885SIGMAR1 3855/4885 |
| US-20210009504-A1 | METHODS FOR PRODUCING (6S,15S)-3,8,13,18-TETRAAZAICOSANE-6,15-DIOL | DHPS, LSS, HSD17B12 | MAOA 720/4885CHRM2 4667/4885SIGMAR1 3855/4885 |
| US-20220009877-A1 | METHODS FOR PRODUCING (6S,15S)-3,8,13,18-TETRAAZAICOSANE-6,15-DIOL | DHPS, LSS, HSD17B12 | MAOA 720/4885CHRM2 4667/4885SIGMAR1 3855/4885 |
| US-20080108706-A1 | Chemical resection of pancreas | RNASE1, AMY2A, IAPP | MAOA 552/4885CHRM2 988/4885SIGMAR1 752/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.