Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | F2 | P00734 | 5/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.42 |
| ▸ | CHRM3 | P20309 | 5/20 | 0.42 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.41 |
| ▸ | DPP4 | P27487 | 3/20 | 0.39 |
| ▸ | CHRM2 | P08172 | 2/20 | 0.39 |
| ▸ | XIAP | P98170 | 1/20 | 0.39 |
| ▸ | MLX | Q9UH92 | 1/20 | 0.39 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.38 |
| ▸ | ACE | P12821 | 1/20 | 0.38 |
| ▸ | FKBP1A | P62942 | 1/20 | 0.38 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.38 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.38 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.38 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.38 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 1/20 | 0.38 |
| ▸ | HTR7 | P34969 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7316700 | 1.00 | F2 (0.42) | F2PRSS1CHRM3TAAR1KMT2A | |
| SCHEMBL7309074 | 0.88 | ACE (0.41) | F2PRSS1CHRM3DPP4DPP8 | |
| SCHEMBL7306032 | 0.88 | F2 (0.49) | F2PRSS1CHRM3FKBP1A | |
| SCHEMBL7306042 | 0.88 | F2 (0.49) | F2PRSS1CHRM3FKBP1A | |
| SCHEMBL7308390 | 0.88 | TACR1 (0.44) | F2PRSS1DPP4XIAPDPP8 | |
| SCHEMBL8083547 | 0.88 | TACR1 (0.44) | F2PRSS1DPP4XIAPDPP8 | |
| SCHEMBL7309067 | 0.88 | ACE (0.41) | F2PRSS1CHRM3DPP4DPP8 | |
| SCHEMBL7308379 | 0.88 | TACR1 (0.44) | F2PRSS1DPP4XIAPDPP8 | |
| SCHEMBL7308557 | 0.87 | CHRM3 (0.44) | F2PRSS1CHRM3DPP4CHRM2 | |
| SCHEMBL7310442 | 0.87 | F2 (0.51) | F2PRSS1CHRM3KMT2ACHRM2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0805147-A1 | Novel N-substituted alpha aminoacid amides as calcium channel modulators | LILLY INDUSTRIES LIMITED (GB) | 1997-11-05 | — | — | EP | disclosed |