Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 5/20 | 0.45 |
| ▸ | PDE3A | Q14432 | 5/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | HPGD | P15428 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ACKR3 | P25106 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7309538 | 0.97 | PDE3B (0.48) | PDE3BPDE3AKDM4EGAAHPGD | |
| SCHEMBL7313037 | 0.89 | PDE3B (0.46) | PDE3BPDE3AKDM4EALDH1A1 | |
| SCHEMBL7313112 | 0.85 | PDE3B (0.40) | PDE3BPDE3AKDM4EGAAHPGD | |
| SCHEMBL7319436 | 0.82 | PDE3B (0.56) | PDE3BPDE3AKDM4EGAAHPGD | |
| SCHEMBL7319732 | 0.78 | PDE3B (0.42) | PDE3BPDE3AKDM4EGAAHPGD | |
| SCHEMBL7318939 | 0.78 | PDE3B (0.50) | PDE3BPDE3A | |
| SCHEMBL7310542 | 0.78 | PDE3B (0.50) | PDE3BPDE3AKDM4EGAAHPGD | |
| SCHEMBL7307748 | 0.78 | PDE3B (0.48) | PDE3BPDE3AKDM4ENPC1SMN1; SMN2 | |
| SCHEMBL7312258 | 0.78 | PDE3B (0.42) | PDE3BPDE3AKDM4EGAAHPGD | |
| SCHEMBL7311818 | 0.76 | PDE3B (0.45) | PDE3BPDE3AKDM4EHPGDALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |