Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 3/20 | 0.42 |
| ▸ | PDE3A | Q14432 | 3/20 | 0.42 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.33 |
| ▸ | NAMPT | P43490 | 1/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | GAA | P10253 | 1/20 | 0.30 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7312258 | 0.85 | PDE3B (0.42) | PDE3BPDE3ALMNANPC1ALOX15 | |
| SCHEMBL7312169 | 0.82 | PDE3B (0.47) | PDE3BPDE3ALMNANPC1ALOX15 | |
| SCHEMBL7307748 | 0.78 | PDE3B (0.48) | PDE3BPDE3ALMNANPC1ALOX15 | |
| SCHEMBL7316751 | 0.78 | PDE3B (0.45) | PDE3BPDE3ANPC1MAPK1HSD17B10 | |
| SCHEMBL7315783 | 0.78 | PDE3B (0.66) | PDE3BPDE3ALMNANPC1ALOX15 | |
| SCHEMBL7313112 | 0.78 | PDE3B (0.40) | PDE3BPDE3ANPC1MAPK1SMN1; SMN2 | |
| SCHEMBL7318331 | 0.78 | PDE3B (0.48) | PDE3BPDE3ALMNANPC1ALOX15 | |
| Acetic Acid SCHEMBL7314774 | 0.76 | PDE3B (0.66) | PDE3BPDE3ALMNANPC1ALOX15 | |
| SCHEMBL7309538 | 0.75 | PDE3B (0.48) | PDE3BPDE3ANPC1MAPK1HSD17B10 | |
| SCHEMBL7313037 | 0.73 | PDE3B (0.46) | PDE3BPDE3ALMNAALDH1A1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |