Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.52 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.52 |
| ▸ | MASP2 | O00187 | 2/20 | 0.33 |
| ▸ | XDH | P47989 | 1/20 | 0.33 |
| ▸ | ACACB | O00763 | 3/20 | 0.32 |
| ▸ | ACACA | Q13085 | 2/20 | 0.32 |
| ▸ | NAAA | Q02083 | 1/20 | 0.32 |
| ▸ | ASAH1 | Q13510 | 1/20 | 0.32 |
| ▸ | RARB | P10826 | 3/20 | 0.31 |
| ▸ | IRAK4 | Q9NWZ3 | 2/20 | 0.31 |
| ▸ | LTA4H | P09960 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 2/20 | 0.30 |
| ▸ | PLK1 | P53350 | 1/20 | 0.30 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.30 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.30 |
| ▸ | SPHK1 | Q9NYA1 | 1/20 | 0.30 |
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7311942 | 0.94 | ITGB3 (0.53) | ITGB3ITGA2BMASP2ACACBIRAK4 | |
| SCHEMBL7304269 | 0.93 | ITGB3 (0.54) | ITGB3ITGA2BIRAK4LTA4H | |
| SCHEMBL7312569 | 0.91 | ITGB3 (0.51) | ITGB3ITGA2BMASP2IRAK4 | |
| SCHEMBL7306414 | 0.91 | ITGB3 (0.51) | ITGB3ITGA2B | |
| SCHEMBL7309280 | 0.91 | ITGB3 (0.51) | ITGB3ITGA2B | |
| SCHEMBL7308125 | 0.90 | ITGB3 (0.52) | ITGB3ITGA2BIRAK4MAPTKMT2A | |
| SCHEMBL7305042 | 0.89 | ITGB3 (0.51) | ITGB3ITGA2BMASP2ACACBNAAA | |
| SCHEMBL7305149 | 0.88 | ITGB3 (0.52) | ITGB3ITGA2BMASP2NAAAIRAK4 | |
| SCHEMBL7304690 | 0.88 | ITGB3 (0.53) | ITGB3ITGA2BIRAK4KMT2A | |
| SCHEMBL7284255 | 0.88 | ITGB3 (0.56) | ITGB3ITGA2BMASP2RARBSPHK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0567966-B1 | Cyclic imino derivatives, medicaments containing these compounds and processes for the production thereof | BOEHRINGER INGELHEIM PHARMA (DE) | 1998-09-02 | — | — | EP | disclosed |
| US-5576444-A | ANTICOAGULANTS | DR. KARL THOMAE GMBH (DE) | 1996-11-19 | — | — | US | disclosed |
| EP-0567966-A1 | Cyclic imino derivatives, medicaments containing these compounds and processes for the production thereof | Dr. Karl Thomae GmbH (DE) | 1993-11-03 | — | — | EP | disclosed |