Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 1/20 | 0.56 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.56 |
| ▸ | RARB | P10826 | 4/20 | 0.38 |
| ▸ | MIF | P14174 | 2/20 | 0.36 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.36 |
| ▸ | MASP2 | O00187 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7282312 | 0.93 | ITGB3 (0.58) | ITGB3ITGA2BMASP2 | |
| SCHEMBL8181277 | 0.93 | ITGB3 (0.52) | ITGB3ITGA2BRARBSPHK1MASP2 | |
| SCHEMBL8186359 | 0.92 | ITGB3 (0.51) | ITGB3ITGA2BRARBSPHK1MASP2 | |
| Lefradafiban SCHEMBL50399 | 0.91 | ITGB3 (0.62) | ITGB3ITGA2BMIFMASP2 | |
| Lefradafiban SCHEMBL7080546 | 0.91 | ITGB3 (0.62) | ITGB3ITGA2BMIFMASP2 | |
| SCHEMBL7284980 | 0.89 | ITGB3 (0.58) | ITGB3ITGA2BMASP2MAPK1SMN1; SMN2 | |
| SCHEMBL7284195 | 0.89 | ITGB3 (0.57) | ITGB3ITGA2BMASP2MAPK1SMN1; SMN2 | |
| SCHEMBL9095585 | 0.88 | ITGB3 (0.49) | ITGB3ITGA2BRARBMASP2 | |
| SCHEMBL7284983 | 0.88 | ITGB3 (0.58) | ITGB3ITGA2BMASP2 | |
| SCHEMBL7316759 | 0.88 | ITGB3 (0.52) | ITGB3ITGA2BRARBSPHK1MASP2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0483667-B1 | Cyclic imino derivatives, process for their preparation and drugs containing them | THOMAE GMBH DR K (DE) | 1998-02-04 | — | — | EP | disclosed |
| US-5541343-A | ANTIAGGLOMERANTS FOR CELLS OR ANTICOAGULANTS | KARL THOMAE GMBH (DE) | 1996-07-30 | — | — | US | disclosed |
| EP-0483667-A2 | Cyclic imino derivatives, process for their preparation and drugs containing them | Dr. Karl Thomae GmbH (DE) | 1992-05-06 | — | — | EP | disclosed |