Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ELANE | P08246 | 1/20 | 0.60 |
| ▸ | C1R | P00736 | 3/20 | 0.51 |
| ▸ | AMY1A | P0DUB6 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.48 |
| ▸ | HPGD | P15428 | 3/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.48 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | NPC1 | O15118 | 2/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | STAT3 | P40763 | 1/20 | 0.47 |
| ▸ | RAB9A | P51151 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | KLK7 | P49862 | 6/20 | 0.47 |
| ▸ | KLK14 | Q9P0G3 | 6/20 | 0.47 |
| ▸ | KLK5 | Q9Y337 | 6/20 | 0.47 |
| ▸ | CTSG | P08311 | 5/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL913690 | 0.84 | ELANE (0.74) | ELANEC1RALDH1A1HPGDKDM4E | |
| SCHEMBL5790698 | 0.84 | C1R (0.72) | ELANEC1RTP53ALDH1A1HPGD | |
| SCHEMBL10018572 | 0.76 | KMT2A (0.52) | ELANEC1RAMY1AALDH1A1HPGD | |
| SCHEMBL5794442 | 0.76 | ELANE (0.71) | ELANEC1RALDH1A1HPGDKDM4E | |
| SCHEMBL9984612 | 0.75 | ELANE (1.00) | ELANEC1RALDH1A1HPGDKDM4E | |
| SCHEMBL30893109 | 0.74 | ALDH1A1 (0.70) | C1RTP53ALDH1A1HPGDKDM4E | |
| SCHEMBL18131027 | 0.74 | ALDH1A1 (0.70) | C1RTP53ALDH1A1HPGDKDM4E | |
| SCHEMBL914556 | 0.73 | C1R (0.72) | ELANEC1RALDH1A1KDM4EKMT2A | |
| SCHEMBL5793015 | 0.73 | KMT2A (0.63) | ELANEC1RTP53ALDH1A1HPGD | |
| SCHEMBL6565665 | 0.72 | TP53 (0.70) | ELANEC1RTP53ALDH1A1HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6180625-B1 | MODULATING AND NORMALIZING AN IMPAIRED HAEMOSTATIC BALANCE IN A MAMMAL, WHICH METHOD COMPRISES ADMINISTERING AN EFFECTIVE AMOUNT OF NOVEL BENZOXAZIN DERIVATIVES; ANTICOAGULANTS | NOVO NORDISK A/S (DK) | 2001-01-30 | — | — | US | claimed |