Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.37 |
| ▸ | MAPT | P10636 | 2/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | ACHE | P22303 | 1/20 | 0.32 |
| ▸ | LIPE | Q05469 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.31 |
| ▸ | POLB | P06746 | 1/20 | 0.31 |
| ▸ | NR4A1 | P22736 | 1/20 | 0.31 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.31 |
| ▸ | POLQ | O75417 | 1/20 | 0.31 |
| ▸ | GLA | P06280 | 1/20 | 0.31 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.31 |
| ▸ | RECQL | P46063 | 1/20 | 0.30 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.30 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.30 |
| ▸ | TP53 | P04637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5381321 | 0.91 | ALDH1A1 (0.42) | ALDH1A1MAPTNPSR1SMN1; SMN2MEN1 | |
| SCHEMBL5376972 | 0.77 | ALDH1A1 (0.45) | ALDH1A1MAPTNPSR1KMT2AKDM4E | |
| SCHEMBL5385244 | 0.75 | DPP4 (0.48) | ALDH1A1MAPTNPSR1KMT2AKDM4E | |
| SCHEMBL5371744 | 0.74 | RAPGEF4 (0.44) | ALDH1A1NPSR1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL5381790 | 0.74 | ALDH1A1 (0.40) | ALDH1A1MAPTNPSR1MEN1KMT2A | |
| Cafenstrole SCHEMBL54625 | 0.73 | KMT2A (0.49) | ALDH1A1MAPTSMN1; SMN2MEN1KMT2A | |
| SCHEMBL5378985 | 0.71 | ALDH1A1 (0.38) | ALDH1A1MAPTNPSR1MEN1KMT2A | |
| SCHEMBL8859187 | 0.70 | F2 (0.40) | ALDH1A1MAPTMEN1KMT2AKDM4E | |
| SCHEMBL9378261 | 0.66 | DPP4 (0.36) | ALDH1A1NPSR1SMN1; SMN2MEN1KMT2A | |
| Cafenstrole SCHEMBL14655384 | 0.65 | KDM4E (0.36) | ALDH1A1KMT2AKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1258480-A1 | Pharmaceutical use of N-Carbamoylazole derivatives | Eisai Co., Ltd. (JP) | 2002-11-20 | — | — | EP | disclosed |