Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 2/20 | 0.33 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.33 |
| ▸ | DRD2 | P14416 | 2/20 | 0.32 |
| ▸ | DRD3 | P35462 | 2/20 | 0.32 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 4/20 | 0.31 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.31 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | NTSR1 | P30989 | 1/20 | 0.31 |
| ▸ | HTT | P42858 | 1/20 | 0.31 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.31 |
| ▸ | NOD2 | Q9HC29 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7312619 | 0.89 | PDE3B (0.33) | PDE3BPDE3ADRD2DRD3ADRA1A | |
| SCHEMBL7316904 | 0.77 | PDE3B (0.38) | PDE3BPDE3AGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL7320607 | 0.75 | PDE4A (0.42) | PDE3BPDE3A | |
| SCHEMBL7319837 | 0.72 | PDE3B (0.37) | PDE3BPDE3AGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL7317240 | 0.70 | PDE3B (0.36) | PDE3BPDE3AGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL7317932 | 0.70 | PDE3B (0.35) | PDE3BPDE3AGAAALDH1A1KMT2A | |
| SCHEMBL7320036 | 0.69 | LMNA (0.35) | SMN1; SMN2ALDH1A1KMT2AMEN1MAPK1 | |
| SCHEMBL7312612 | 0.69 | PDE4A (0.39) | PDE3BPDE3AGAASMN1; SMN2ALDH1A1 | |
| SCHEMBL7318846 | 0.66 | PDE3B (0.41) | PDE3BPDE3A | |
| SCHEMBL7318346 | 0.64 | PDE4A (0.51) | PDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4739056-A | ENZYME INHIBITORS | SYNTEX (U.S.A.) INC. (US) | 1988-04-19 | — | — | US | disclosed |