Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.39 |
| ▸ | HPGD | P15428 | 4/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.38 |
| ▸ | RAB9A | P51151 | 3/20 | 0.38 |
| ▸ | LMNA | P02545 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.38 |
| ▸ | HTR1A | P08908 | 2/20 | 0.37 |
| ▸ | HTR2A | P28223 | 2/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.36 |
| ▸ | USP2 | O75604 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ATM | Q13315 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7312248 | 0.87 | MAPT (0.39) | MAPTHPGDNPSR1ALDH1A1RAB9A | |
| SCHEMBL7312643 | 0.87 | MAPT (0.38) | MAPTHPGDNPSR1ALDH1A1RAB9A | |
| SCHEMBL7316945 | 0.79 | ALDH1A1 (0.36) | MAPTHPGDNPSR1ALDH1A1RAB9A | |
| SCHEMBL7316959 | 0.74 | ALDH1A1 (0.35) | MAPTHPGDNPSR1ALDH1A1RAB9A | |
| SCHEMBL7314876 | 0.73 | MAOB (0.44) | MAPTALDH1A1RAB9ALMNAPKM | |
| SCHEMBL7317901 | 0.71 | ALDH1A1 (0.44) | MAPTHPGDNPSR1ALDH1A1RAB9A | |
| SCHEMBL7316993 | 0.69 | MAPT (0.34) | MAPTHPGDNPSR1ALDH1A1RAB9A | |
| SCHEMBL7309722 | 0.68 | SIRT3 (0.44) | MAPTALDH1A1LMNATDP1MAPK1 | |
| SCHEMBL7321019 | 0.68 | MAPK1 (0.39) | MAPTALDH1A1RAB9ALMNATDP1 | |
| SCHEMBL7320606 | 0.68 | PDE3B (0.37) | MAPTHPGDNPSR1ALDH1A1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |