Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.36 |
| ▸ | RAB9A | P51151 | 3/20 | 0.36 |
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | HPGD | P15428 | 3/20 | 0.35 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.35 |
| ▸ | POLB | P06746 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HTR1A | P08908 | 3/20 | 0.34 |
| ▸ | HTR2A | P28223 | 3/20 | 0.34 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | CA12 | O43570 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7312241 | 0.88 | MAPT (0.37) | ALDH1A1RAB9AMAPTHPGDNPSR1 | |
| SCHEMBL7312638 | 0.87 | MAPT (0.35) | ALDH1A1RAB9AMAPTHPGDNPSR1 | |
| SCHEMBL7316959 | 0.82 | ALDH1A1 (0.35) | ALDH1A1RAB9AMAPTHPGDNPSR1 | |
| SCHEMBL7316951 | 0.79 | MAPT (0.39) | ALDH1A1RAB9AMAPTHPGDNPSR1 | |
| SCHEMBL7314872 | 0.72 | NPC1 (0.40) | ALDH1A1RAB9AMAPTLMNATDP1 | |
| SCHEMBL7312257 | 0.72 | ALDH1A1 (0.37) | ALDH1A1RAB9AMAPTHPGDNPSR1 | |
| SCHEMBL7313632 | 0.71 | ATM (0.39) | ALDH1A1RAB9AMAPTNPSR1LMNA | |
| SCHEMBL7312650 | 0.71 | CA12 (0.35) | ALDH1A1RAB9AMAPTHPGDNPSR1 | |
| SCHEMBL7316989 | 0.69 | MAPT (0.32) | ALDH1A1RAB9AMAPTHPGDNPSR1 | |
| SCHEMBL7312248 | 0.68 | MAPT (0.39) | ALDH1A1RAB9AMAPTHPGDNPSR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |