Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | TP53 | P04637 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2089745 | 0.77 | — | — | |
| SCHEMBL2089742 | 0.77 | — | — | |
| SCHEMBL7317059 | 0.76 | — | — | |
| SCHEMBL11094602 | 0.76 | ALDH1A1 (0.43) | ALDH1A1 | |
| SCHEMBL2622620 | 0.76 | — | — | |
| SCHEMBL7314285 | 0.74 | ALDH1A1 (0.43) | ALDH1A1TP53TDP1HDAC8 | |
| SCHEMBL7321865 | 0.72 | — | — | |
| SCHEMBL7325372 | 0.70 | ALDH1A1 (0.36) | ALDH1A1TP53TDP1HDAC8 | |
| SCHEMBL9985989 | 0.67 | — | — | |
| SCHEMBL12334229 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4845100-A | WITH HYPOTENSIVE AND ANTIINFLAMMATORY ACTIVITY | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1989-07-04 | — | — | US | disclosed |
| EP-0202760-A2 | Carbostyril derivatives and salts thereof, processes for preparing the same and cardiotonic composition containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1986-11-26 | — | — | EP | disclosed |