Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PLG | P00747 | 1/20 | 0.55 |
| ▸ | IP6K2 | Q9UHH9 | 3/20 | 0.54 |
| ▸ | FLT3 | P36888 | 2/20 | 0.54 |
| ▸ | MAOB | P27338 | 2/20 | 0.54 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.54 |
| ▸ | CYP19A1 | P11511 | 1/20 | 0.54 |
| ▸ | CYP1B1 | Q16678 | 4/20 | 0.53 |
| ▸ | CYP1A1 | P04798 | 3/20 | 0.53 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.53 |
| ▸ | ABCC1 | P33527 | 2/20 | 0.53 |
| ▸ | KDM1A | O60341 | 1/20 | 0.53 |
| ▸ | XDH | P47989 | 1/20 | 0.53 |
| ▸ | IPMK | Q8NFU5 | 1/20 | 0.53 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.51 |
| ▸ | NPC1 | O15118 | 2/20 | 0.51 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.51 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.51 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7315691 | 0.88 | CYP1B1 (0.69) | IP6K2FLT3MAOBMKNK2CYP19A1 | |
| SCHEMBL7317399 | 0.85 | EGFR (0.52) | — | |
| SCHEMBL26117114 | 0.77 | CYP1B1 (0.86) | PLGIP6K2FLT3MAOBMKNK2 | |
| SCHEMBL29845342 | 0.77 | CYP1B1 (0.86) | PLGIP6K2FLT3MAOBMKNK2 | |
| SCHEMBL1421382 | 0.77 | CYP1B1 (0.86) | PLGIP6K2FLT3MAOBMKNK2 | |
| SCHEMBL27907057 | 0.76 | CYP1B1 (0.84) | PLGIP6K2FLT3MAOBMKNK2 | |
| Methane SCHEMBL27890494 | 0.76 | CYP1B1 (0.84) | PLGIP6K2FLT3MAOBMKNK2 | |
| Velutin SCHEMBL29928535 | 0.75 | CYP1B1 (0.86) | PLGIP6K2FLT3MAOBMKNK2 | |
| Velutin SCHEMBL5804380 | 0.75 | CYP1B1 (0.86) | PLGIP6K2FLT3MAOBMKNK2 | |
| SCHEMBL7310271 | 0.74 | EGFR (0.57) | CYP1B1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832886-B1 | Flavon derivatives, process for their preparation, and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2002-11-13 | — | — | EP | disclosed |
| US-5889003-A | PHOSPHODIESTERASE INHIBITOR | ADIR ET COMPAGNIE (FR) | 1999-03-30 | — | — | US | disclosed |
| EP-0832886-A1 | Flavon derivatives, process for their preparation, and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1998-04-01 | — | — | EP | disclosed |