Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EGFR | P00533 | 17/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7310271 | 0.89 | EGFR (0.57) | EGFR | |
| SCHEMBL7315691 | 0.86 | CYP1B1 (0.69) | — | |
| Dimethylformamide SCHEMBL7317423 | 0.85 | PLG (0.55) | — | |
| SCHEMBL7309697 | 0.82 | CYP1B1 (0.58) | EGFR | |
| SCHEMBL7318625 | 0.80 | CYP1B1 (0.56) | EGFR | |
| SCHEMBL7311286 | 0.80 | CYP1B1 (0.56) | — | |
| SCHEMBL7310036 | 0.79 | CYP1B1 (0.55) | EGFR | |
| SCHEMBL8356014 | 0.78 | CYP1B1 (0.53) | — | |
| SCHEMBL7307218 | 0.77 | PPARG (0.52) | EGFR | |
| SCHEMBL8429583 | 0.77 | CYP1B1 (0.67) | EGFR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0832886-B1 | Flavon derivatives, process for their preparation, and pharmaceutical compositions containing them | SERVIER LAB (FR) | 2002-11-13 | — | — | EP | disclosed |
| US-5889003-A | PHOSPHODIESTERASE INHIBITOR | ADIR ET COMPAGNIE (FR) | 1999-03-30 | — | — | US | disclosed |
| EP-0832886-A1 | Flavon derivatives, process for their preparation, and pharmaceutical compositions containing them | ADIR ET COMPAGNIE (FR) | 1998-04-01 | — | — | EP | disclosed |