SCHEMBL7317499

SCHEMBL7317499

Cc1c(CCCCCCC(=O)Cl)ccc([N+](=O)[O-])c1C=O

nearest known ligand 0.40

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 4/20 0.35
TDP1 Q9NUW8 1/20 0.35
ACLY P53396 1/20 0.33
BCHE P06276 1/20 0.33
ACHE P22303 1/20 0.33
KMT2A Q03164 2/20 0.32
LMNA P02545 1/20 0.32
MAPK1 P28482 1/20 0.32
PDK1 Q15118 1/20 0.32
FBP1 P09467 1/20 0.32
NPC1 O15118 1/20 0.32
RAB9A P51151 1/20 0.32
FAAH O00519 1/20 0.31
TSHR P16473 3/20 0.31
BACE1 P56817 1/20 0.31
ATM Q13315 1/20 0.31
TXNRD1 Q16881 1/20 0.31

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7318824 0.89 F13A1 (0.40) TDP1KMT2AFBP1
Hydrochloric Acid SCHEMBL7317507 0.88 F13A1 (0.39) TDP1KMT2AFBP1
SCHEMBL7311366 0.86 ACLY (0.38) ALDH1A1TDP1ACLYBCHEACHE
SCHEMBL7310125 0.85 ALDH1A1 (0.47) ALDH1A1TDP1BCHEACHEKMT2A
SCHEMBL7313318 0.84 ERN1 (0.39) ALDH1A1BCHEACHEKMT2ALMNA
SCHEMBL7312039 0.78 ALDH1A1 (0.39) ALDH1A1TDP1KMT2ALMNA
SCHEMBL7315717 0.78 ACLY (0.38) ALDH1A1TDP1ACLYKMT2ALMNA
SCHEMBL7315333 0.77 ACLY (0.42) ALDH1A1TDP1ACLYKMT2AFBP1
SCHEMBL7318441 0.76 ALDH1A1 (0.48) ALDH1A1TDP1KMT2AMAPK1TSHR
SCHEMBL7307845 0.76 MAPT (0.37) ALDH1A1KMT2AMAPK1TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4670434-A ANTICOAGULANT, INOTROPIC AGENT SYNTEX (U.S.A.) INC. (US) 1987-06-02 US disclosed