Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NAMPT | P43490 | 9/20 | 0.47 |
| ▸ | MMP1 | P03956 | 7/20 | 0.46 |
| ▸ | MMP9 | P14780 | 7/20 | 0.46 |
| ▸ | MMP13 | P45452 | 7/20 | 0.46 |
| ▸ | ADAM17 | P78536 | 5/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.41 |
| ▸ | GAA | P10253 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7322044 | 0.92 | NAMPT (0.47) | NAMPTMMP1MMP9MMP13ADAM17 | |
| SCHEMBL7324868 | 0.91 | MMP9 (0.50) | NAMPTMMP1MMP9MMP13ADAM17 | |
| SCHEMBL7322273 | 0.89 | NAMPT (0.48) | NAMPTMMP1MMP9MMP13ADAM17 | |
| SCHEMBL7313738 | 0.88 | NAMPT (0.43) | NAMPTMMP1MMP9MMP13ADAM17 | |
| SCHEMBL7316225 | 0.88 | NAMPT (0.47) | NAMPTMMP1MMP9MMP13ADAM17 | |
| SCHEMBL7316589 | 0.88 | NAMPT (0.47) | NAMPTMMP1MMP9MMP13ADAM17 | |
| SCHEMBL7314654 | 0.86 | MMP9 (0.46) | NAMPTMMP1MMP9MMP13ADAM17 | |
| SCHEMBL7318942 | 0.86 | MMP13 (0.52) | NAMPTMMP1MMP9MMP13ADAM17 | |
| SCHEMBL7320609 | 0.84 | MMP9 (0.49) | NAMPTMMP1MMP9MMP13ADAM17 | |
| SCHEMBL7318589 | 0.83 | NAMPT (0.39) | NAMPTMMP1MMP9MMP13ADAM17 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5929097-A | INHIBIT TUMOR NECROSIS FACTOR-ALPHA CONVERTING ENZYME | AMERICAN CYANAMID COMPANY (US) | 1999-07-27 | — | — | US | disclosed |