Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADAM17 | P78536 | 20/20 | 0.68 |
| ▸ | MMP13 | P45452 | 10/20 | 0.63 |
| ▸ | MMP9 | P14780 | 8/20 | 0.60 |
| ▸ | MMP1 | P03956 | 5/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3938344 | 0.82 | ADAM17 (1.00) | ADAM17MMP13MMP9MMP1 | |
| SCHEMBL6656433 | 0.80 | ADAM17 (0.73) | ADAM17MMP13MMP9MMP1 | |
| SCHEMBL6659884 | 0.78 | ADAM17 (1.00) | ADAM17MMP13MMP9MMP1 | |
| SCHEMBL3947817 | 0.76 | ADAM17 (1.00) | ADAM17MMP13MMP9MMP1 | |
| SCHEMBL3949526 | 0.76 | ADAM17 (1.00) | ADAM17MMP13MMP9MMP1 | |
| SCHEMBL7422448 | 0.76 | ADAM17 (0.78) | ADAM17MMP13MMP9MMP1 | |
| SCHEMBL6654744 | 0.75 | ADAM17 (0.80) | ADAM17MMP13MMP9MMP1 | |
| SCHEMBL6657039 | 0.75 | ADAM17 (0.80) | ADAM17MMP13MMP9MMP1 | |
| SCHEMBL3941409 | 0.75 | ADAM17 (0.80) | ADAM17MMP13MMP9MMP1 | |
| SCHEMBL3940267 | 0.75 | ADAM17 (1.00) | ADAM17MMP13MMP9MMP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6340691-B1 | TREATMENT OF ARTHRITIS, TUMOR METASTASIS, TISSUE ULCERATION, ABNORMAL WOUND HEALING, PERIODONTAL DISEASE, BONE DISEASE, DIABETES (INSULIN RESISTANCE) AND HIV INFECTION | AMERICAN CYANAMID COMPANY | 2002-01-22 | — | — | US | disclosed |