Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.59 |
| ▸ | ALDH1A1 | P00352 | 13/20 | 0.54 |
| ▸ | HTT | P42858 | 3/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.54 |
| ▸ | GAA | P10253 | 1/20 | 0.54 |
| ▸ | PKM | P14618 | 1/20 | 0.52 |
| ▸ | GFER | P55789 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.49 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 2/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.48 |
| ▸ | TTR | P02766 | 1/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30135880 | 1.00 | SMN1; SMN2 (0.59) | SMN1; SMN2ALDH1A1HTTLMNAGAA | |
| SCHEMBL31090163 | 0.90 | SMN1; SMN2 (0.61) | SMN1; SMN2ALDH1A1HTTLMNAGAA | |
| SCHEMBL11439108 | 0.88 | SMN1; SMN2 (0.54) | SMN1; SMN2ALDH1A1HTTLMNAGAA | |
| SCHEMBL499343 | 0.87 | SMN1; SMN2 (0.58) | SMN1; SMN2ALDH1A1HTTLMNAGAA | |
| SCHEMBL8973887 | 0.86 | SMN1; SMN2 (0.57) | SMN1; SMN2ALDH1A1HTTLMNAGAA | |
| SCHEMBL8867003 | 0.86 | SMN1; SMN2 (0.57) | SMN1; SMN2ALDH1A1HTTLMNAGAA | |
| SCHEMBL2742574 | 0.84 | ALDH1A1 (0.61) | SMN1; SMN2ALDH1A1HTTLMNAGAA | |
| SCHEMBL3720228 | 0.84 | SMN1; SMN2 (0.59) | SMN1; SMN2ALDH1A1HTTLMNAGAA | |
| SCHEMBL8867007 | 0.84 | SMN1; SMN2 (0.67) | SMN1; SMN2ALDH1A1HTTLMNAGAA | |
| SCHEMBL16233087 | 0.83 | SMN1; SMN2 (0.61) | SMN1; SMN2ALDH1A1HTTLMNAGAA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5534626-A | SELECTIVE MUSCARINIC RECEPTOR ANTAGONIST INTERMEDIATES | PFIZER INC. (US) | 1996-07-09 | — | — | US | disclosed |
| US-5410046-A | Selective muscarinic receptor antagonists | PFIZER INC. (US) | 1995-04-25 | — | — | US | disclosed |
| US-5231104-A | Anticholinergic | PFIZER INC. (US) | 1993-07-27 | — | — | US | disclosed |
| EP-0350309-B1 | PIPERIDINE DERIVATIVES | Pfizer Limited (GB) | 1992-11-11 | — | — | EP | disclosed |
| US-5089505-A | Anticholinergic agents | PFIZER INC. (US) | 1992-02-18 | — | — | US | disclosed |
| EP-0350309-A1 | Piperidine derivatives | Pfizer Limited (GB) | 1990-01-10 | — | — | EP | disclosed |
| US-4438131-A | CARDIOVASCULAR DISORDERS | BASF AKTIENGESELLSCHAFT (DE) | 1984-03-20 | — | — | US | disclosed |
| EP-0064158-A1 | Omega-cyano-1, omega-diphenyl azalcane derivatives, their preparation and pharmaceutical preparations containing them | BASF Aktiengesellschaft (DE) | 1982-11-10 | — | — | EP | disclosed |