Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 3/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.34 |
| ▸ | FFAR4 | Q5NUL3 | 3/20 | 0.33 |
| ▸ | FFAR1 | O14842 | 2/20 | 0.33 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.32 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.32 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.32 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.32 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.32 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.32 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 2/20 | 0.31 |
| ▸ | NPC1 | O15118 | 1/20 | 0.30 |
| ▸ | FBP1 | P09467 | 1/20 | 0.30 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7307198 | 0.89 | FFAR4 (0.40) | MAPTALDH1A1FFAR4FFAR1 | |
| Hydrochloric Acid SCHEMBL7317635 | 0.88 | FFAR4 (0.40) | MAPTALDH1A1FFAR4FFAR1 | |
| SCHEMBL7307867 | 0.86 | MAPT (0.34) | MAPTALDH1A1LMNANPC1FBP1 | |
| SCHEMBL7317668 | 0.85 | PDK2 (0.37) | MAPTALDH1A1FFAR4FFAR1GRIN2D | |
| SCHEMBL7307272 | 0.84 | BRD4 (0.39) | MAPTALDH1A1LMNANPC1FBP1 | |
| SCHEMBL7309678 | 0.83 | THRB (0.34) | MAPTALDH1A1LMNAFBP1SMN1; SMN2 | |
| SCHEMBL7305457 | 0.81 | MCL1 (0.36) | MAPTALDH1A1FFAR1NPC1 | |
| SCHEMBL7307818 | 0.81 | GRIN2D (0.34) | MAPTALDH1A1FFAR4FFAR1GRIN2D | |
| SCHEMBL7318661 | 0.80 | PTGDR2 (0.39) | MAPTALDH1A1FFAR1 | |
| SCHEMBL7309626 | 0.78 | SIRT5 (0.43) | MAPTALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |