Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 11/20 | 0.55 |
| ▸ | MKNK2 | Q9HBH9 | 10/20 | 0.55 |
| ▸ | CA12 | O43570 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.52 |
| ▸ | CA2 | P00918 | 1/20 | 0.52 |
| ▸ | ESR1 | P03372 | 1/20 | 0.52 |
| ▸ | CA7 | P43166 | 1/20 | 0.52 |
| ▸ | CA9 | Q16790 | 1/20 | 0.52 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.52 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.52 |
| ▸ | RARA | P10276 | 1/20 | 0.46 |
| ▸ | RARB | P10826 | 1/20 | 0.46 |
| ▸ | RARG | P13631 | 1/20 | 0.46 |
| ▸ | IDO1 | P14902 | 2/20 | 0.44 |
| ▸ | FYN | P06241 | 1/20 | 0.43 |
| ▸ | CDC7 | O00311 | 1/20 | 0.42 |
| ▸ | DBF4 | Q9UBU7 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6132537 | 0.84 | MKNK1 (0.52) | MKNK1MKNK2IDO1FYNMAPT | |
| SCHEMBL7322460 | 0.82 | MKNK1 (0.53) | MKNK1MKNK2CA12CA1CA2 | |
| SCHEMBL7350299 | 0.79 | HRH3 (0.65) | MKNK1MKNK2ESR1ESR2 | |
| SCHEMBL7326365 | 0.79 | HRH3 (0.64) | MKNK1MKNK2ESR1ESR2 | |
| SCHEMBL6134597 | 0.79 | MKNK1 (0.48) | MKNK1MKNK2RARARARBRARG | |
| SCHEMBL7312737 | 0.79 | HRH3 (0.64) | MKNK1MKNK2ESR1ESR2 | |
| SCHEMBL7324143 | 0.78 | HRH3 (0.53) | MKNK1MKNK2ESR1ESR2 | |
| SCHEMBL7326853 | 0.77 | MKNK1 (0.57) | MKNK1MKNK2MAPT | |
| SCHEMBL6134929 | 0.77 | MKNK1 (0.47) | MKNK1MKNK2 | |
| SCHEMBL6135144 | 0.77 | MKNK1 (0.47) | MKNK1MKNK2FYN |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6232290-B1 | FUNGICIDES AGAINST PNEUMOCYSTIS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-15 | — | — | US | disclosed |