Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MKNK1 | Q9BUB5 | 10/20 | 0.52 |
| ▸ | MKNK2 | Q9HBH9 | 10/20 | 0.52 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.46 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.46 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | TBXAS1 | P24557 | 1/20 | 0.44 |
| ▸ | FYN | P06241 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | HTT | P42858 | 1/20 | 0.43 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.43 |
| ▸ | IDO1 | P14902 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.42 |
| ▸ | TSHR | P16473 | 1/20 | 0.42 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7318292 | 0.90 | MKNK1 (0.61) | MKNK1MKNK2FYNHPGDHTT | |
| SCHEMBL7321701 | 0.90 | MKNK1 (0.61) | MKNK1MKNK2FYNHPGDHTT | |
| SCHEMBL7324198 | 0.90 | MKNK1 (0.61) | MKNK1MKNK2FYNHPGDHTT | |
| SCHEMBL7324612 | 0.90 | MKNK1 (0.61) | MKNK1MKNK2FYNHPGDHTT | |
| SCHEMBL6132847 | 0.88 | MKNK1 (0.51) | MKNK1MKNK2TSHR | |
| SCHEMBL7350299 | 0.86 | HRH3 (0.65) | MKNK1MKNK2KCNH2HRH3ALDH1A1 | |
| SCHEMBL7326365 | 0.86 | HRH3 (0.64) | MKNK1MKNK2KCNH2HRH3ALDH1A1 | |
| SCHEMBL7312737 | 0.86 | HRH3 (0.64) | MKNK1MKNK2KCNH2HRH3ALDH1A1 | |
| SCHEMBL7324143 | 0.85 | HRH3 (0.53) | MKNK1MKNK2KCNH2HRH3TBXAS1 | |
| SCHEMBL7317643 | 0.84 | MKNK1 (0.55) | MKNK1MKNK2FYNIDO1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6884868-B1 | Cyclic hexapeptides having antibiotic activity | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2005-04-26 | — | — | US | disclosed |
| EP-1173472-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-01-23 | — | — | EP | disclosed |
| WO-2000064927-A1 | CYCLIC HEXAPEPTIDES HAVING ANTIBIOTIC ACTIVITY | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2000-11-02 | — | — | WO | disclosed |