Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 11/20 | 0.65 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.65 |
| ▸ | MKNK1 | Q9BUB5 | 7/20 | 0.53 |
| ▸ | MKNK2 | Q9HBH9 | 7/20 | 0.53 |
| ▸ | ESR1 | P03372 | 1/20 | 0.50 |
| ▸ | ESR2 | Q92731 | 1/20 | 0.50 |
| ▸ | CACNA1F | O60840 | 3/20 | 0.49 |
| ▸ | BCHE | P06276 | 3/20 | 0.49 |
| ▸ | CACNA1D | Q01668 | 3/20 | 0.49 |
| ▸ | CACNA1S | Q13698 | 3/20 | 0.49 |
| ▸ | CACNA1C | Q13936 | 3/20 | 0.49 |
| ▸ | HRH4 | Q9H3N8 | 3/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.48 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.48 |
| ▸ | HRH1 | P35367 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7326365 | 0.99 | HRH3 (0.64) | HRH3KCNH2MKNK1MKNK2ESR1 | |
| SCHEMBL7312737 | 0.99 | HRH3 (0.64) | HRH3KCNH2MKNK1MKNK2ESR1 | |
| SCHEMBL7324143 | 0.92 | HRH3 (0.53) | HRH3KCNH2MKNK1MKNK2ESR1 | |
| SCHEMBL7326853 | 0.91 | MKNK1 (0.57) | HRH3KCNH2MKNK1MKNK2KDM4E | |
| SCHEMBL6132537 | 0.86 | MKNK1 (0.52) | HRH3KCNH2MKNK1MKNK2ALDH1A1 | |
| SCHEMBL7319729 | 0.86 | KDM4E (0.53) | HRH3KCNH2MKNK1MKNK2KDM4E | |
| SCHEMBL7313001 | 0.86 | KDM4E (0.53) | HRH3KCNH2MKNK1MKNK2KDM4E | |
| SCHEMBL7350288 | 0.83 | HRH3 (0.63) | HRH3KCNH2ESR1ESR2CACNA1F | |
| SCHEMBL7326355 | 0.82 | HRH3 (0.62) | HRH3KCNH2ESR1ESR2CACNA1F | |
| SCHEMBL7312730 | 0.82 | HRH3 (0.62) | HRH3KCNH2ESR1ESR2CACNA1F |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6232290-B1 | FUNGICIDES AGAINST PNEUMOCYSTIS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2001-05-15 | — | — | US | disclosed |