Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LAP3 | P28838 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7378197 | 0.83 | FDPS (0.43) | LAP3 | |
| SCHEMBL11031855 | 0.75 | KDM4E (0.31) | — | |
| SCHEMBL14930256 | 0.71 | CA1 (0.30) | — | |
| SCHEMBL14779384 | 0.71 | CA1 (0.30) | — | |
| Ammonia Solution, Strong SCHEMBL25247344 | 0.70 | — | — | |
| SCHEMBL27842700 | 0.70 | EPHX1 (0.31) | — | |
| SCHEMBL10364856 | 0.70 | — | — | |
| SCHEMBL14139030 | 0.70 | — | — | |
| SCHEMBL14793049 | 0.70 | — | — | |
| SCHEMBL2327079 | 0.69 | SMN1; SMN2 (0.35) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5212163-A | Phosphonate dipeptide or tripeptide derivatives as collagenase inhibitors for treatment of connective tissue disorders | BEECHAM GROUP P.L.C. (GB) | 1993-05-18 | — | — | US | disclosed |
| WO-1991015507-A1 | PHOSPHONOPEPTIDES WITH COLLAGENASE INHIBITING ACTIVITY | BEECHAM GROUP PLC (GB) | 1991-10-17 | — | — | WO | disclosed |
| EP-0401963-A1 | Phosphonopeptides with collagenase inhibiting activity | Beecham Group p.l.c. (GB) | 1990-12-12 | — | — | EP | disclosed |