Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 7/20 | 0.43 |
| ▸ | LAP3 | P28838 | 2/20 | 0.36 |
| ▸ | LPAR1 | Q92633 | 1/20 | 0.35 |
| ▸ | LPAR3 | Q9UBY5 | 1/20 | 0.35 |
| ▸ | SMPD1 | P17405 | 3/20 | 0.34 |
| ▸ | S1PR2 | O95136 | 5/20 | 0.33 |
| ▸ | S1PR1 | P21453 | 5/20 | 0.33 |
| ▸ | S1PR3 | Q99500 | 5/20 | 0.33 |
| ▸ | S1PR4 | O95977 | 4/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7317945 | 0.83 | LAP3 (0.33) | LAP3 | |
| SCHEMBL5286793 | 0.75 | EPHX1 (0.40) | SMPD1 | |
| SCHEMBL8911416 | 0.73 | CA2 (0.40) | — | |
| SCHEMBL2326465 | 0.73 | CA2 (0.40) | — | |
| SCHEMBL27525293 | 0.73 | EPHX1 (0.34) | — | |
| SCHEMBL28037185 | 0.73 | EPHX1 (0.34) | — | |
| SCHEMBL17651980 | 0.70 | EPHX1 (0.33) | — | |
| SCHEMBL14778630 | 0.70 | EPHX1 (0.33) | — | |
| SCHEMBL11031855 | 0.70 | KDM4E (0.31) | — | |
| SCHEMBL5275588 | 0.69 | EPHX1 (0.46) | SMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5212163-A | Phosphonate dipeptide or tripeptide derivatives as collagenase inhibitors for treatment of connective tissue disorders | BEECHAM GROUP P.L.C. (GB) | 1993-05-18 | — | — | US | disclosed |
| EP-0401963-A1 | Phosphonopeptides with collagenase inhibiting activity | Beecham Group p.l.c. (GB) | 1990-12-12 | — | — | EP | disclosed |