Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADRB2 | P07550 | 1/20 | 0.51 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.51 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.51 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.46 |
| ▸ | MEN1 | O00255 | 2/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | AR | P10275 | 1/20 | 0.46 |
| ▸ | USP2 | O75604 | 1/20 | 0.46 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | CASP1 | P29466 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.46 |
| ▸ | SLCO1B3 | Q9NPD5 | 1/20 | 0.46 |
| ▸ | SLCO1B1 | Q9Y6L6 | 1/20 | 0.46 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.45 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5381741 | 0.84 | ADRB2 (0.71) | ADRB2ADRB1ADRB3MAPK1KMT2A | |
| SCHEMBL7316789 | 0.81 | ADRB2 (0.48) | ADRB2ADRB1ADRB3MAPK1KMT2A | |
| SCHEMBL7310711 | 0.80 | ADRB2 (0.47) | ADRB2ADRB1ADRB3MAPK1KMT2A | |
| SCHEMBL16004487 | 0.79 | AR (0.67) | MAPK1KMT2AMEN1LMNAAR | |
| SCHEMBL7313195 | 0.78 | AR (0.43) | ADRB2ADRB1ADRB3MAPK1KMT2A | |
| SCHEMBL24948597 | 0.78 | AR (0.56) | ADRB2ADRB1ADRB3MAPK1KMT2A | |
| SCHEMBL30781975 | 0.77 | ADRB2 (0.52) | ADRB2ADRB1ADRB3MAPK1KMT2A | |
| SCHEMBL13191159 | 0.76 | AR (0.67) | MAPK1KMT2AMEN1LMNAAR | |
| SCHEMBL12988346 | 0.76 | AR (0.67) | MAPK1KMT2AMEN1LMNAAR | |
| SCHEMBL13190959 | 0.76 | AR (0.67) | MAPK1KMT2AMEN1LMNAAR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4258062-A | ISOPRENALINE ANTAGONISTS EFFECTING HEART RATE AND BLOOD PRESSURE | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1981-03-24 | — | — | US | disclosed |
| US-4171370-A | Phenoxy-amino-propanols | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 1979-10-16 | — | — | US | disclosed |