Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | EPHX2 | P34913 | 7/20 | 0.45 |
| ▸ | CYP11B1 | P15538 | 2/20 | 0.38 |
| ▸ | CYP11B2 | P19099 | 2/20 | 0.38 |
| ▸ | PTK2 | Q05397 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.36 |
| ▸ | CA9 | Q16790 | 1/20 | 0.36 |
| ▸ | NAMPT | P43490 | 1/20 | 0.36 |
| ▸ | F9 | P00740 | 1/20 | 0.36 |
| ▸ | F10 | P00742 | 1/20 | 0.36 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | IRAK4 | Q9NWZ3 | 1/20 | 0.35 |
| ▸ | USP8 | P40818 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.35 |
| ▸ | LHCGR | P22888 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7318316 | 0.75 | CRACR2A (0.51) | EPHX2PTK2CA12CA1CA2 | |
| SCHEMBL7323905 | 0.74 | EPHX2 (0.54) | EPHX2IRAK4MAPT | |
| SCHEMBL7325689 | 0.67 | MAPT (0.47) | EPHX2CYP11B1CYP11B2CA12CA1 | |
| SCHEMBL7239521 | 0.66 | PKM (0.48) | EPHX2CYP11B1CYP11B2CA12CA1 | |
| SCHEMBL7328104 | 0.64 | NPY5R (0.53) | CYP11B1CYP11B2CA12CA1CA2 | |
| SCHEMBL7233236 | 0.64 | USP8 (0.48) | EPHX2CYP11B1CYP11B2CA12CA1 | |
| SCHEMBL7315513 | 0.64 | CA1 (0.52) | EPHX2CYP11B1CYP11B2CA12CA1 | |
| SCHEMBL7234719 | 0.64 | EPHX2 (0.60) | EPHX2CYP11B1CYP11B2CA12CA1 | |
| SCHEMBL7320959 | 0.63 | BCHE (0.42) | CYP11B1CYP11B2CA12CA1CA2 | |
| SCHEMBL7327417 | 0.62 | USP8 (0.46) | CYP11B1CYP11B2CA12CA1CA2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20010044445-A1 | AZOLE INHIBITORS OF CYTOKINE PRODUCTION | ABBOTT LABORATORIES | 2001-11-22 | — | — | US | claimed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010044445-A1 | AZOLE INHIBITORS OF CYTOKINE PRODUCTION | IL5, IL2, IL4 | EPHX2 732/4885CYP11B1 26/4885CYP11B2 18/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.