Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE3B | Q13370 | 19/20 | 0.48 |
| ▸ | PDE3A | Q14432 | 19/20 | 0.48 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.36 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.36 |
| ▸ | BLM | P54132 | 1/20 | 0.36 |
| ▸ | NPC1 | O15118 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7306886 | 0.85 | PDE3B (0.48) | PDE3BPDE3ALMNATSHRNPC1 | |
| SCHEMBL7312688 | 0.84 | PDE3B (0.51) | PDE3BPDE3A | |
| SCHEMBL7316240 | 0.81 | PDE3B (0.71) | PDE3BPDE3A | |
| SCHEMBL7317020 | 0.80 | PDE3B (0.51) | PDE3BPDE3ALMNATSHRNPC1 | |
| SCHEMBL7318939 | 0.79 | PDE3B (0.50) | PDE3BPDE3A | |
| SCHEMBL7312634 | 0.79 | PDE3B (0.44) | PDE3BPDE3ANPC1 | |
| SCHEMBL7319732 | 0.78 | PDE3B (0.42) | PDE3BPDE3ALMNATSHRNPC1 | |
| SCHEMBL7313823 | 0.76 | PDE3B (0.53) | PDE3BPDE3A | |
| SCHEMBL7318826 | 0.75 | PDE3B (0.58) | PDE3BPDE3A | |
| SCHEMBL7317488 | 0.75 | PDE3B (0.47) | PDE3BPDE3A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |