Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.46 |
| ▸ | MAPT | P10636 | 5/20 | 0.46 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | PRKDC | P78527 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | THRA | P10827 | 1/20 | 0.38 |
| ▸ | THRB | P10828 | 1/20 | 0.38 |
| ▸ | PRSS1 | P07477 | 3/20 | 0.37 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | HPGD | P15428 | 1/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27118714 | 0.89 | ALDH1A1 (0.47) | ALDH1A1MAPTKDM4ECYP3A4ALOX15 | |
| SCHEMBL7321047 | 0.89 | ALDH1A1 (0.47) | ALDH1A1MAPTKDM4ECYP3A4ALOX15 | |
| Hydrochloric Acid SCHEMBL7318415 | 0.88 | ALDH1A1 (0.46) | ALDH1A1MAPTKDM4ECYP3A4ALOX15 | |
| SCHEMBL7309433 | 0.86 | ALDH1A1 (0.44) | ALDH1A1MAPTKDM4ECYP3A4ALOX15 | |
| SCHEMBL7311275 | 0.86 | MAPT (0.45) | ALDH1A1MAPTKDM4ECYP3A4ALOX15 | |
| SCHEMBL10376957 | 0.85 | ALDH1A1 (0.45) | ALDH1A1MAPTKDM4ECYP3A4ALOX15 | |
| SCHEMBL7312215 | 0.85 | MAPT (0.44) | ALDH1A1MAPTKDM4ECYP3A4ALOX15 | |
| SCHEMBL7313873 | 0.83 | MAPT (0.45) | ALDH1A1MAPTKDM4ECYP3A4ALOX15 | |
| SCHEMBL7315491 | 0.82 | MAPT (0.46) | ALDH1A1MAPTKDM4ECYP3A4ALOX15 | |
| SCHEMBL7319139 | 0.82 | ALDH1A1 (0.46) | ALDH1A1MAPTKDM4ECYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-4670434-A | ANTICOAGULANT, INOTROPIC AGENT | SYNTEX (U.S.A.) INC. (US) | 1987-06-02 | — | — | US | disclosed |