Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LAP3 | P28838 | 4/20 | 0.49 |
| ▸ | ANPEP | P15144 | 3/20 | 0.49 |
| ▸ | RNPEP | Q9H4A4 | 2/20 | 0.49 |
| ▸ | DNPEP | Q9ULA0 | 2/20 | 0.49 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.38 |
| ▸ | MMP2 | P08253 | 2/20 | 0.37 |
| ▸ | MMP3 | P08254 | 1/20 | 0.37 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.37 |
| ▸ | LTA4H | P09960 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 2/20 | 0.36 |
| ▸ | RAB9A | P51151 | 2/20 | 0.36 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CTRB1 | P17538 | 1/20 | 0.36 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8729343 | 0.88 | LAP3 (0.45) | LAP3ANPEPRNPEPDNPEPSLC15A1 | |
| SCHEMBL7328902 | 0.84 | LAP3 (0.49) | LAP3ANPEPRNPEPDNPEPSLC15A1 | |
| SCHEMBL8882496 | 0.80 | PSEN1 (0.38) | LAP3ANPEPRNPEPDNPEPMMP2 | |
| SCHEMBL9064384 | 0.75 | LAP3 (0.55) | LAP3ANPEPRNPEPDNPEPSLC15A1 | |
| SCHEMBL7360777 | 0.74 | HTT (0.44) | — | |
| SCHEMBL6225204 | 0.74 | LAP3 (0.48) | LAP3ANPEPRNPEPDNPEPSLC15A1 | |
| SCHEMBL5872214 | 0.74 | LAP3 (0.48) | LAP3ANPEPRNPEPDNPEPSLC15A1 | |
| SCHEMBL5404893 | 0.73 | LAP3 (0.47) | LAP3ANPEPRNPEPDNPEPSLC15A1 | |
| SCHEMBL8159887 | 0.73 | LAP3 (0.47) | LAP3ANPEPRNPEPDNPEPSLC15A1 | |
| SCHEMBL21012314 | 0.73 | LAP3 (0.62) | LAP3ANPEPRNPEPDNPEPSLC15A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0558673-A1 | RETROVIRAL PROTEASE INHIBITORS. | MONSANTO CO (US) | 1993-09-08 | — | — | EP | disclosed |
| WO-1992008699-A1 | RETROVIRAL PROTEASE INHIBITORS | MONSANTO COMPANY (US) | 1992-05-29 | — | — | WO | disclosed |