Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LAP3 | P28838 | 4/20 | 0.49 |
| ▸ | ANPEP | P15144 | 4/20 | 0.49 |
| ▸ | RNPEP | Q9H4A4 | 3/20 | 0.49 |
| ▸ | DNPEP | Q9ULA0 | 3/20 | 0.49 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.40 |
| ▸ | CSNK1E | P49674 | 1/20 | 0.39 |
| ▸ | ALPI | P09923 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 1/20 | 0.38 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.38 |
| ▸ | XIAP | P98170 | 1/20 | 0.38 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.38 |
| ▸ | SLC6A2 | P23975 | 2/20 | 0.37 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.37 |
| ▸ | MAOA | P21397 | 1/20 | 0.37 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.37 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.37 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.37 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.37 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.37 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7318484 | 0.84 | LAP3 (0.49) | LAP3ANPEPRNPEPDNPEPSLC15A1 | |
| SCHEMBL8729343 | 0.74 | LAP3 (0.45) | LAP3ANPEPRNPEPDNPEPSLC15A1 | |
| SCHEMBL6225271 | 0.74 | LAP3 (0.51) | LAP3ANPEPRNPEPDNPEPSLC15A1 | |
| SCHEMBL9076303 | 0.69 | CSNK1E (0.64) | LAP3ANPEPRNPEPDNPEPSLC15A1 | |
| SCHEMBL9076300 | 0.69 | CSNK1E (0.64) | LAP3ANPEPRNPEPDNPEPSLC15A1 | |
| Bicarbonate SCHEMBL7838533 | 0.68 | SLC15A1 (0.56) | LAP3ANPEPRNPEPDNPEPSLC15A1 | |
| SCHEMBL3614651 | 0.67 | SPPL2A (0.52) | LAP3ANPEPRNPEPDNPEPSLC15A1 | |
| SCHEMBL7412831 | 0.66 | SLC15A1 (0.50) | LAP3ANPEPRNPEPDNPEPSLC15A1 | |
| SCHEMBL7412834 | 0.66 | SLC15A1 (0.50) | LAP3ANPEPRNPEPDNPEPSLC15A1 | |
| SCHEMBL23752456 | 0.66 | SLC6A2 (0.61) | LAP3ANPEPRNPEPDNPEPSLC15A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5622949-A | AIDS THERAPY | G. D. SEARLE & CO. (US) | 1997-04-22 | — | — | US | disclosed |
| EP-0558630-A1 | RETROVIRAL PROTEASE INHIBITORS | MONSANTO COMPANY (US) | 1993-09-08 | — | — | EP | disclosed |
| EP-0558603-A1 | RETROVIRAL PROTEASE INHIBITORS | MONSANTO COMPANY (US) | 1993-09-08 | — | — | EP | disclosed |
| EP-0558657-A1 | RETROVIRAL PROTEASE INHIBITORS. | MONSANTO CO (US) | 1993-09-08 | — | — | EP | disclosed |
| EP-0558673-A1 | RETROVIRAL PROTEASE INHIBITORS. | MONSANTO CO (US) | 1993-09-08 | — | — | EP | disclosed |
| WO-1992008701-A1 | RETROVIRAL PROTEASE INHIBITORS | MONSANTO COMPANY (US) | 1992-05-29 | — | — | WO | disclosed |
| WO-1992008700-A1 | RETROVIRAL PROTEASE INHIBITORS | MONSANTO COMPANY (US) | 1992-05-29 | — | — | WO | disclosed |
| WO-1992008688-A1 | RETROVIRAL PROTEASE INHIBITORS | MONSANTO COMPANY (US) | 1992-05-29 | — | — | WO | disclosed |
| WO-1992008699-A1 | RETROVIRAL PROTEASE INHIBITORS | MONSANTO COMPANY (US) | 1992-05-29 | — | — | WO | disclosed |