Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ITGB3 | P05106 | 5/20 | 0.33 |
| ▸ | ITGA2B | P08514 | 5/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 7/20 | 0.32 |
| ▸ | MAPT | P10636 | 6/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.32 |
| ▸ | NPC1 | O15118 | 4/20 | 0.32 |
| ▸ | RAB9A | P51151 | 4/20 | 0.32 |
| ▸ | GAA | P10253 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 3/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 3/20 | 0.31 |
| ▸ | MEN1 | O00255 | 1/20 | 0.31 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.31 |
| ▸ | GFER | P55789 | 1/20 | 0.31 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | CASP3 | P42574 | 1/20 | 0.30 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.30 |
| ▸ | RELA | Q04206 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7316347 | 0.97 | MCHR1 (0.33) | ITGB3ITGA2BSMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL7392480 | 0.95 | ITGB3 (0.33) | ITGB3ITGA2BSMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL7311917 | 0.91 | MAPT (0.43) | ITGB3ITGA2BSMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL7318811 | 0.88 | MAPT (0.43) | ITGB3ITGA2BSMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL7392907 | 0.87 | MAPT (0.43) | ITGB3ITGA2BSMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL7387131 | 0.86 | SMN1; SMN2 (0.33) | ITGB3ITGA2BSMN1; SMN2MAPTALDH1A1 | |
| SCHEMBL7396723 | 0.86 | SMN1; SMN2 (0.33) | SMN1; SMN2MAPTALDH1A1NPC1RAB9A | |
| SCHEMBL7390233 | 0.85 | ITGB3 (0.49) | ITGB3ITGA2BMCHR1 | |
| SCHEMBL7390232 | 0.85 | ITGB3 (0.49) | ITGB3ITGA2BMCHR1 | |
| SCHEMBL7386944 | 0.85 | ITGB3 (0.43) | ITGB3ITGA2BSMN1; SMN2MAPTNPC1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760364-B1 | Amidine derivatives and platelet aggregation inhibitor containing the same | MITSUI CHEMICALS INC (JP) | 2000-07-19 | — | — | EP | disclosed |
| US-5719145-A | FIBRINOGEN ANTAGONIST FOR TREATMENT OF THROMBOSIS, RESTENOSIS AFTER ANGIOPLASTY OR CORONARY RECANALIZATION; WATER SOLUBILITY, ORAL ADMINISTRATION | MITSUI TOATSU CHEMICALS, INC. (JP) | 1998-02-17 | — | — | US | disclosed |
| EP-0760364-A2 | Amidine derivatives and platelet aggregation inhibitor containing the same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1997-03-05 | — | — | EP | disclosed |