Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MCHR1 | Q99705 | 12/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.32 |
| ▸ | MAPT | P10636 | 3/20 | 0.32 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.32 |
| ▸ | NPC1 | O15118 | 2/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | DRD2 | P14416 | 1/20 | 0.32 |
| ▸ | DRD3 | P35462 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 3/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.31 |
| ▸ | THRB | P10828 | 1/20 | 0.31 |
| ▸ | PKM | P14618 | 1/20 | 0.31 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.31 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7318519 | 0.97 | ITGB3 (0.33) | MCHR1SMN1; SMN2MAPTALDH1A1NPC1 | |
| SCHEMBL7392480 | 0.92 | ITGB3 (0.33) | SMN1; SMN2MAPTALDH1A1NPC1RAB9A | |
| SCHEMBL7318811 | 0.91 | MAPT (0.43) | MCHR1SMN1; SMN2MAPTALDH1A1NPC1 | |
| SCHEMBL7311917 | 0.88 | MAPT (0.43) | MCHR1SMN1; SMN2MAPTALDH1A1NPC1 | |
| SCHEMBL7395083 | 0.87 | MAPT (0.43) | MCHR1SMN1; SMN2MAPTALDH1A1NPC1 | |
| SCHEMBL7387131 | 0.86 | SMN1; SMN2 (0.33) | SMN1; SMN2MAPTALDH1A1NPC1RAB9A | |
| SCHEMBL7396723 | 0.86 | SMN1; SMN2 (0.33) | SMN1; SMN2MAPTALDH1A1NPC1RAB9A | |
| SCHEMBL7394841 | 0.85 | ITGB3 (0.42) | MCHR1ITGB3ITGA2B | |
| SCHEMBL7388125 | 0.85 | ITGB3 (0.47) | MCHR1ITGB3ITGA2B | |
| SCHEMBL7394843 | 0.85 | ITGB3 (0.42) | MCHR1ITGB3ITGA2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0760364-B1 | Amidine derivatives and platelet aggregation inhibitor containing the same | MITSUI CHEMICALS INC (JP) | 2000-07-19 | — | — | EP | disclosed |
| US-5719145-A | FIBRINOGEN ANTAGONIST FOR TREATMENT OF THROMBOSIS, RESTENOSIS AFTER ANGIOPLASTY OR CORONARY RECANALIZATION; WATER SOLUBILITY, ORAL ADMINISTRATION | MITSUI TOATSU CHEMICALS, INC. (JP) | 1998-02-17 | — | — | US | disclosed |
| EP-0760364-A2 | Amidine derivatives and platelet aggregation inhibitor containing the same | MITSUI TOATSU CHEMICALS, Inc. (JP) | 1997-03-05 | — | — | EP | disclosed |