Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.70 |
| ▸ | MEN1 | O00255 | 2/20 | 0.70 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.60 |
| ▸ | LMNA | P02545 | 1/20 | 0.60 |
| ▸ | DRD2 | P14416 | 1/20 | 0.60 |
| ▸ | ACHE | P22303 | 1/20 | 0.60 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.60 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.60 |
| ▸ | DRD3 | P35462 | 1/20 | 0.60 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.60 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.58 |
| ▸ | BRD4 | O60885 | 2/20 | 0.58 |
| ▸ | NPC1 | O15118 | 1/20 | 0.58 |
| ▸ | TP53 | P04637 | 1/20 | 0.56 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL7323563 | 0.98 | KMT2A (0.68) | KMT2AMEN1SMN1; SMN2MAPK1POLB | |
| SCHEMBL24162893 | 0.88 | MEN1 (0.58) | KMT2AMEN1SMN1; SMN2MAPK1POLB | |
| SCHEMBL28686671 | 0.84 | LMNA (0.59) | KMT2AMEN1SMN1; SMN2MAPK1LMNA | |
| SCHEMBL10790461 | 0.83 | KMT2A (0.77) | KMT2AMEN1SMN1; SMN2MAPK1POLB | |
| SCHEMBL2926341 | 0.83 | KMT2A (0.77) | KMT2AMEN1SMN1; SMN2MAPK1POLB | |
| SCHEMBL7945842 | 0.81 | KMT2A (0.74) | KMT2AMEN1SMN1; SMN2MAPK1POLB | |
| SCHEMBL20094150 | 0.81 | SMN1; SMN2 (0.55) | KMT2AMEN1SMN1; SMN2POLBDRD2 | |
| SCHEMBL11639395 | 0.81 | ALDH1A1 (0.61) | KMT2AMEN1SMN1; SMN2LMNABRD4 | |
| SCHEMBL15656703 | 0.80 | ALDH1A1 (0.52) | KMT2AMEN1SMN1; SMN2POLBLMNA | |
| SCHEMBL1559022 | 0.80 | ALDH1A1 (0.52) | KMT2AMEN1SMN1; SMN2POLBDRD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0293925-A2 | Compound active in cardiovascular therapy | SIMES, SOCIETA ITALIANA MEDICINALI E SINTETICI, S.P.A. (IT) | 1988-12-07 | — | — | EP | disclosed |