Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 1/20 | 0.40 |
| ▸ | FAAH | O00519 | 2/20 | 0.38 |
| ▸ | TRPV1 | Q8NER1 | 1/20 | 0.38 |
| ▸ | F7 | P08709 | 1/20 | 0.38 |
| ▸ | F3 | P13726 | 1/20 | 0.38 |
| ▸ | CNR1 | P21554 | 5/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7319223 | 1.00 | ALDH1A1 (0.40) | ALDH1A1TSHRFAAHTRPV1F7 | |
| SCHEMBL28676449 | 0.91 | FAAH (0.50) | TSHRFAAHTRPV1F7F3 | |
| SCHEMBL7296489 | 0.91 | TSHR (0.40) | ALDH1A1TSHRFAAHTRPV1F7 | |
| SCHEMBL7296491 | 0.91 | TSHR (0.40) | ALDH1A1TSHRFAAHTRPV1F7 | |
| SCHEMBL7294697 | 0.88 | FAAH (0.41) | ALDH1A1TSHRFAAHTRPV1F7 | |
| SCHEMBL7294690 | 0.88 | FAAH (0.41) | ALDH1A1TSHRFAAHTRPV1F7 | |
| SCHEMBL2119332 | 0.85 | TSHR (0.35) | TSHR | |
| SCHEMBL2119328 | 0.85 | TSHR (0.35) | TSHR | |
| SCHEMBL6949363 | 0.82 | FAAH (0.50) | TSHRFAAHTRPV1F7F3 | |
| SCHEMBL6949367 | 0.82 | FAAH (0.50) | TSHRFAAHTRPV1F7F3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0202760-A2 | Carbostyril derivatives and salts thereof, processes for preparing the same and cardiotonic composition containing the same | OTSUKA PHARMACEUTICAL CO., LTD. (JP) | 1986-11-26 | — | — | EP | disclosed |