Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | HPGD | P15428 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | CAPN1 | P07384 | 1/20 | 0.38 |
| ▸ | CAPN2 | P17655 | 1/20 | 0.38 |
| ▸ | TERT | O14746 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9683565 | 0.91 | L3MBTL1 (0.38) | MEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL7314499 | 0.91 | HRH4 (0.41) | MEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL7311781 | 0.89 | TLR2 (0.38) | — | |
| Hydrochloric Acid SCHEMBL9683593 | 0.89 | TLR2 (0.38) | — | |
| SCHEMBL7309636 | 0.86 | TLR2 (0.41) | MEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL7320312 | 0.86 | L3MBTL1 (0.39) | — | |
| SCHEMBL7312123 | 0.85 | MEN1 (0.43) | MEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL7310277 | 0.85 | CYP3A4 (0.42) | ALDH1A1 | |
| SCHEMBL7319953 | 0.84 | L3MBTL1 (0.39) | MEN1ALDH1A1HPGDKMT2A | |
| SCHEMBL7307856 | 0.84 | HRH4 (0.42) | MEN1ALDH1A1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0592367-A2 | Phosphono/biaryl substituted dipeptide derivatives | CIBA-GEIGY AG (CH) | 1994-04-13 | — | — | EP | disclosed |
| US-5294632-A | Diuretics and vasorelaxants | CIBA-GEIGY CORPORATION (US) | 1994-03-15 | — | — | US | disclosed |
| EP-0511940-A2 | Phosphono/biaryl substituted dipeptide derivatives | CIBA-GEIGY AG (CH) | 1992-11-04 | — | — | EP | disclosed |
| US-5155100-A | Treating cardiovascular disorders in mammals | CIBA-GEIGY CORPORATION (US) | 1992-10-13 | — | — | US | disclosed |