Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR2 | O60603 | 7/20 | 0.41 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | HPGD | P15428 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | LPAR1 | Q92633 | 2/20 | 0.38 |
| ▸ | BCHE | P06276 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9683565 | 0.95 | L3MBTL1 (0.38) | TLR2L3MBTL1MEN1ALDH1A1HPGD | |
| SCHEMBL7314444 | 0.95 | TLR2 (0.39) | TLR2L3MBTL1MEN1ALDH1A1HPGD | |
| SCHEMBL7322726 | 0.93 | TLR2 (0.40) | TLR2L3MBTL1MEN1ALDH1A1HPGD | |
| SCHEMBL7320387 | 0.92 | MMEL1 (0.44) | TLR2L3MBTL1BCHE | |
| SCHEMBL7319307 | 0.92 | MMEL1 (0.44) | TLR2L3MBTL1BCHE | |
| SCHEMBL7311781 | 0.90 | TLR2 (0.38) | TLR2 | |
| Hydrochloric Acid SCHEMBL9683593 | 0.89 | TLR2 (0.38) | TLR2 | |
| SCHEMBL7319953 | 0.89 | L3MBTL1 (0.39) | TLR2L3MBTL1MEN1ALDH1A1HPGD | |
| SCHEMBL7321253 | 0.88 | L3MBTL1 (0.39) | TLR2L3MBTL1MEN1ALDH1A1HPGD | |
| SCHEMBL7319346 | 0.86 | MEN1 (0.40) | MEN1ALDH1A1HPGDKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0592367-A2 | Phosphono/biaryl substituted dipeptide derivatives | CIBA-GEIGY AG (CH) | 1994-04-13 | — | — | EP | disclosed |
| US-5294632-A | Diuretics and vasorelaxants | CIBA-GEIGY CORPORATION (US) | 1994-03-15 | — | — | US | disclosed |
| US-5155100-A | Treating cardiovascular disorders in mammals | CIBA-GEIGY CORPORATION (US) | 1992-10-13 | — | — | US | disclosed |