Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 7/20 | 0.38 |
| ▸ | MEN1 | O00255 | 4/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.38 |
| ▸ | THRB | P10828 | 2/20 | 0.38 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.36 |
| ▸ | POLB | P06746 | 2/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | FPR1 | P21462 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7326240 | 0.80 | KDM4E (0.45) | KDM4EALDH1A1MAPTGAAPOLB | |
| SCHEMBL15069034 | 0.74 | MEN1 (0.42) | SMN1; SMN2KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL20533689 | 0.73 | KDM4E (0.43) | SMN1; SMN2KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL20596629 | 0.73 | ALDH1A1 (0.47) | SMN1; SMN2KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL24739338 | 0.73 | KDM4E (0.38) | SMN1; SMN2KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL3689482 | 0.71 | KDM4E (0.41) | SMN1; SMN2KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL4822612 | 0.69 | KDM4E (0.47) | SMN1; SMN2KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL25397343 | 0.69 | MAPK1 (0.50) | SMN1; SMN2KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL25395707 | 0.68 | KDM4E (0.42) | SMN1; SMN2KDM4EMEN1KMT2AALDH1A1 | |
| SCHEMBL20985955 | 0.68 | KDM4E (0.53) | SMN1; SMN2KDM4EMEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5028605-A | Antispasmodic, bronchodilators, uterine relaxants, cardiac analeptics, neurosedatives | L'UNIVERSITE DE MONTPELLIER I (FR) | 1991-07-02 | — | — | US | disclosed |
| EP-0348392-A1 | 8-ALKYLAMINOIMIDAZO[1,2-A]PYRAZINES AND DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION IN THERAPY | Université Montpellier I (FR) | 1990-01-03 | — | — | EP | disclosed |
| WO-1988004298-A1 | 8-ALKYLAMINOIMIDAZO[1,2-A]PYRAZINES AND DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION IN THERAPY | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1988-06-16 | — | — | WO | disclosed |