Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.48 |
| ▸ | LMNA | P02545 | 3/20 | 0.48 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | AR | P10275 | 1/20 | 0.43 |
| ▸ | CRHBP | P24387 | 1/20 | 0.42 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.42 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7361622 | 0.88 | ALDH1A1 (0.56) | ALDH1A1LMNAKMT2A | |
| SCHEMBL7328791 | 0.87 | ALDH1A1 (0.49) | ALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL7319630 | 0.85 | ALDH1A1 (0.47) | ALDH1A1LMNAKMT2AMEN1KDM4E | |
| SCHEMBL7324184 | 0.82 | SMN1; SMN2 (0.46) | ALDH1A1LMNAKMT2AMEN1 | |
| SCHEMBL7328061 | 0.81 | TP53 (0.43) | ALDH1A1LMNAKMT2AKDM4ETRPM8 | |
| SCHEMBL7331811 | 0.80 | SNCA (0.54) | ALDH1A1LMNANPSR1 | |
| SCHEMBL15695027 | 0.80 | ALDH1A1 (0.47) | ALDH1A1LMNAKMT2AMEN1KDM4E | |
| SCHEMBL1694355 | 0.80 | ALDH1A1 (0.48) | ALDH1A1LMNAKMT2AMEN1KDM4E | |
| SCHEMBL13729336 | 0.80 | KDM4E (0.48) | ALDH1A1LMNAKMT2AMEN1KDM4E | |
| SCHEMBL13729340 | 0.80 | KDM4E (0.48) | ALDH1A1LMNAKMT2AMEN1KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5075304-A | Nervous system disorders | NOVO NORDISK A/S (DK) | 1991-12-24 | — | — | US | disclosed |
| EP-0344943-A1 | Imidazoquinoxaline compounds and their preparation and use | NOVO NORDISK A/S (DK) | 1989-12-06 | — | — | EP | disclosed |