Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.44 |
| ▸ | CES2 | O00748 | 1/20 | 0.44 |
| ▸ | ACHE | P22303 | 1/20 | 0.44 |
| ▸ | CES1 | P23141 | 1/20 | 0.44 |
| ▸ | TRPM8 | Q7Z2W7 | 1/20 | 0.44 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 1/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | AR | P10275 | 2/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.41 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7361629 | 0.90 | ALDH1A1 (0.53) | ALDH1A1LMNARXFP1KMT2ARAB9A | |
| SCHEMBL7328793 | 0.88 | L3MBTL1 (0.47) | ALDH1A1LMNAKDM4EL3MBTL1CES2 | |
| SCHEMBL7319626 | 0.85 | ALDH1A1 (0.48) | ALDH1A1LMNAKDM4ETRPM8KMT2A | |
| SCHEMBL7324191 | 0.84 | SMN1; SMN2 (0.43) | ALDH1A1LMNAKDM4EL3MBTL1CES2 | |
| SCHEMBL7328071 | 0.83 | RXFP1 (0.45) | ALDH1A1KDM4EL3MBTL1CES2ACHE | |
| SCHEMBL7331816 | 0.83 | SNCA (0.52) | ALDH1A1LMNAKDM4EL3MBTL1KMT2A | |
| SCHEMBL7319642 | 0.81 | SMN1; SMN2 (0.42) | ALDH1A1LMNAKDM4EL3MBTL1CES2 | |
| SCHEMBL8470246 | 0.80 | CES2 (0.45) | ALDH1A1LMNAKDM4EL3MBTL1CES2 | |
| SCHEMBL13729331 | 0.79 | ALDH1A1 (0.51) | ALDH1A1LMNAKDM4EL3MBTL1TRPM8 | |
| SCHEMBL15695027 | 0.79 | ALDH1A1 (0.47) | ALDH1A1LMNAKDM4EL3MBTL1TRPM8 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5075304-A | Nervous system disorders | NOVO NORDISK A/S (DK) | 1991-12-24 | — | — | US | disclosed |
| EP-0344943-A1 | Imidazoquinoxaline compounds and their preparation and use | NOVO NORDISK A/S (DK) | 1989-12-06 | — | — | EP | disclosed |