Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 10/20 | 0.49 |
| ▸ | REN | P00797 | 2/20 | 0.49 |
| ▸ | BACE1 | P56817 | 3/20 | 0.44 |
| ▸ | KLK5 | Q9Y337 | 1/20 | 0.40 |
| ▸ | ECE1 | P42892 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7328959 | 1.00 | CTSD (0.49) | CTSDRENBACE1KLK5ECE1 | |
| SCHEMBL10377257 | 0.85 | CTSD (0.39) | CTSDRENBACE1ECE1 | |
| SCHEMBL7328082 | 0.81 | CTSD (0.55) | CTSDRENBACE1KLK5ECE1 | |
| SCHEMBL7328076 | 0.81 | CTSD (0.55) | CTSDRENBACE1KLK5ECE1 | |
| SCHEMBL7328595 | 0.80 | CTSD (0.65) | CTSDRENBACE1 | |
| SCHEMBL7328968 | 0.80 | CTSD (0.54) | CTSDRENBACE1ECE1 | |
| SCHEMBL7320103 | 0.78 | CTSD (0.59) | CTSDRENECE1 | |
| SCHEMBL7332555 | 0.78 | CTSD (0.58) | CTSDRENBACE1ECE1 | |
| SCHEMBL7327030 | 0.77 | CTSD (0.61) | CTSDRENBACE1 | |
| SCHEMBL10954138 | 0.77 | ACE (0.45) | ECE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1990000399-A1 | RETROVIRAL PROTEASE BINDING PEPTIDES | SMITHKLINE BECKMAN CORPORATION (US) | 1990-01-25 | — | — | WO | disclosed |
| EP-0352000-A2 | Retroviral protease binding peptides | SMITHKLINE BEECHAM CORPORATION (US) | 1990-01-24 | — | — | EP | disclosed |