Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSD | P07339 | 7/20 | 0.54 |
| ▸ | REN | P00797 | 5/20 | 0.54 |
| ▸ | BACE1 | P56817 | 3/20 | 0.51 |
| ▸ | ECE1 | P42892 | 2/20 | 0.50 |
| ▸ | MME | P08473 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7328076 | 0.99 | CTSD (0.55) | CTSDRENBACE1ECE1MME | |
| SCHEMBL7328082 | 0.99 | CTSD (0.55) | CTSDRENBACE1ECE1MME | |
| SCHEMBL7332555 | 0.97 | CTSD (0.58) | CTSDRENBACE1ECE1MME | |
| SCHEMBL7320103 | 0.96 | CTSD (0.59) | CTSDRENECE1MME | |
| SCHEMBL7332534 | 0.92 | CTSD (0.54) | CTSDRENBACE1 | |
| SCHEMBL7331052 | 0.91 | CTSD (0.63) | CTSDRENBACE1 | |
| SCHEMBL7329209 | 0.90 | CTSD (0.64) | CTSDRENBACE1 | |
| SCHEMBL7324774 | 0.89 | CTSD (0.61) | CTSDRENBACE1 | |
| SCHEMBL7332756 | 0.87 | REN (0.48) | CTSDRENBACE1 | |
| SCHEMBL7330753 | 0.86 | REN (0.49) | CTSDRENBACE1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-1990000399-A1 | RETROVIRAL PROTEASE BINDING PEPTIDES | SMITHKLINE BECKMAN CORPORATION (US) | 1990-01-25 | — | — | WO | disclosed |
| EP-0352000-A2 | Retroviral protease binding peptides | SMITHKLINE BEECHAM CORPORATION (US) | 1990-01-24 | — | — | EP | disclosed |