Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | TSHR | P16473 | 3/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | HSP90AB1 | P08238 | 1/20 | 0.36 |
| ▸ | PPIA | P62937 | 6/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | RECQL | P46063 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7370142 | 0.75 | NR4A2 (0.41) | MAPTKMT2ANPSR1LMNAGAA | |
| SCHEMBL7366401 | 0.72 | HDAC1 (0.43) | MAPTTSHR | |
| SCHEMBL7317314 | 0.71 | NPC1 (0.44) | KMT2AMEN1 | |
| SCHEMBL7372051 | 0.70 | HDAC1 (0.39) | MAPTTSHR | |
| SCHEMBL7319691 | 0.70 | MAPT (0.46) | MAPTKMT2ATSHRNPSR1HSP90AB1 | |
| SCHEMBL7376615 | 0.67 | EPHX2 (0.39) | KMT2ALMNAMEN1 | |
| SCHEMBL7366313 | 0.67 | PDPK1 (0.40) | — | |
| SCHEMBL7528270 | 0.66 | MAPT (0.65) | MAPTKMT2ATSHRNPSR1PPIA | |
| SCHEMBL7265245 | 0.66 | MAPT (0.47) | MAPTKMT2ATSHRLMNAGAA | |
| SCHEMBL7374066 | 0.65 | S1PR3 (0.40) | MAPTKMT2ATSHRLMNAMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0280956-B1 | THIAZOLIDINE DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1992-10-21 | — | — | EP | claimed |
| US-4857537-A | PREVENTING AMNESIA | ONO PHARMACEUTICAL CO., LTD. (JP) | 1989-08-15 | — | — | US | claimed |
| EP-0280956-A1 | Thiazolidine derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1988-09-07 | — | — | EP | claimed |