Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 2/20 | 0.45 |
| ▸ | F2 | P00734 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.40 |
| ▸ | PREP | P48147 | 1/20 | 0.38 |
| ▸ | FAP | Q12884 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | RECQL | P46063 | 1/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.36 |
| ▸ | PKM | P14618 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7291931 | 0.83 | MAPT (0.49) | MAPTTSHRF2 | |
| SCHEMBL7319691 | 0.81 | MAPT (0.46) | MAPTTSHRKMT2APREPLMNA | |
| SCHEMBL8306791 | 0.80 | MAPT (0.46) | MAPTTSHRF2KMT2APREP | |
| SCHEMBL769700 | 0.77 | MAPT (0.45) | MAPTTSHRF2KMT2A | |
| SCHEMBL8994595 | 0.77 | F2 (0.43) | MAPTTSHRF2KMT2AFAP | |
| SCHEMBL7266943 | 0.76 | DPP4 (0.56) | KMT2ALMNAGAA | |
| SCHEMBL8994550 | 0.76 | MAPT (0.40) | MAPTTSHRKMT2ALMNAGAA | |
| SCHEMBL7265842 | 0.75 | KMT2A (0.50) | KMT2ALMNAGAA | |
| SCHEMBL7265258 | 0.74 | BCHE (0.43) | PREPFAP | |
| SCHEMBL7267072 | 0.74 | DPP4 (0.59) | PREP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-5340832-A | Prolinal derivatives useful for treating amnesia | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-08-23 | — | — | US | claimed |
| EP-0268190-B1 | PROLINAL DERIVATIVES | ONO PHARMACEUTICAL CO., LTD. (JP) | 1993-06-16 | — | — | EP | claimed |
| EP-0268190-A1 | Prolinal derivatives | ONO PHARMACEUTICAL CO., LTD. (JP) | 1988-05-25 | — | — | EP | claimed |
| US-5340832-A | Prolinal derivatives useful for treating amnesia | ONO PHARMACEUTICAL CO., LTD. (JP) | 1994-08-23 | — | — | US | disclosed |